# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5173004 | 41 | Activity | 0 | ALA5167932 | Dde | Homo sapiens | |||||
2. | ALA5173004 | 41 | Activity | 0 | ALA5167930 | Active | ||||||
3. | ALA5173004 | 41 | Activity | 0 | ALA5167929 | Active | ||||||
4. | ALA5173004 | 41 | Activity | 0 | ALA5167928 | Active | ||||||
5. | ALA5173004 | 41 | Activity | 0 | ALA5167927 | Non-Toxic | ||||||
6. | ALA5173004 | 41 | TGI | = | 73 | % | ALA5167926 | % | Homo sapiens | |||
7. | ALA5173004 | 41 | F | = | 7.25 | % | ALA5167924 | % | ||||
8. | ALA5173004 | 41 | Vdss | = | 62.5 | L/Kg | ALA5167922 | L.kg-1 | ||||
9. | ALA5173004 | 41 | CL | = | 310 | ml/min.kg | ALA5167921 | mL.min-1.kg-1 | ||||
10. | ALA5173004 | 41 | AUC | = | 65.3 | hr/ng/ml | ALA5167920 | ng.hr.mL-1 | ||||
11. | ALA5173004 | 41 | AUC | = | 173 | hr/ng/ml | ALA5167919 | ng.hr.mL-1 | ||||
12. | ALA5173004 | 41 | Cmax | = | 8.22 | ng/ml | ALA5167917 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
13. | ALA5173004 | 41 | t1/2 | = | 7.51 | hr | ALA5167915 | hr | ||||
14. | ALA5173004 | 41 | t1/2 | = | 2.58 | hr | ALA5167914 | hr | ||||
15. | ALA5173004 | 41 | IC50 | = | 23.9 | nM | ALA5167913 | 7.62 | nM | Homo sapiens | ||
16. | ALA5173004 | 41 | PPB | = | 99.7 | % | ALA5167912 | % | ||||
17. | ALA5173004 | 41 | PPB | = | 98.6 | % | ALA5167911 | % | ||||
18. | ALA5173004 | 41 | CLH | = | 30.7 | ml/min/g | ALA5167910 | mL.min-1.g-1 | ||||
19. | ALA5173004 | 41 | CLH | = | 227 | ml/min/g | ALA5167909 | mL.min-1.g-1 | ||||
20. | ALA5173004 | 41 | t1/2 | = | 68.4 | min | ALA5167908 | hr |