# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5173613 | 2c; KR-25210 | Stability | 0 | ALA5146862 | Stable | % | |||||
2. | ALA5173613 | 2c; KR-25210 | Stability | 0 | ALA5146861 | Stable | % | |||||
3. | ALA5173613 | 2c; KR-25210 | AUC | = | 0.2 | microg.hr/mL | ALA5146860 | ng.hr.mL-1 | ||||
4. | ALA5173613 | 2c; KR-25210 | AUClast | = | 0.18 | microg.hr/mL | ALA5146859 | ng.hr.mL-1 | ||||
5. | ALA5173613 | 2c; KR-25210 | t1/2 | = | 8.89 | hr | ALA5146858 | hr | ||||
6. | ALA5173613 | 2c; KR-25210 | Cmax | = | 0.02 | ug ml-1 | ALA5146857 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
7. | ALA5173613 | 2c; KR-25210 | Tmax | = | 3.5 | hr | ALA5146856 | hr | ||||
8. | ALA5173613 | 2c; KR-25210 | INH | = | 11.9 | % | ALA5146855 | % | Homo sapiens | |||
9. | ALA5173613 | 2c; KR-25210 | INH | = | 1.26 | % | ALA5146854 | % | Homo sapiens | |||
10. | ALA5173613 | 2c; KR-25210 | INH | = | 3.24 | % | ALA5146853 | % | Homo sapiens | |||
11. | ALA5173613 | 2c; KR-25210 | INH | = | 7.19 | % | ALA5146852 | % | Homo sapiens | |||
12. | ALA5173613 | 2c; KR-25210 | INH | = | 7.46 | % | ALA5146851 | % | Homo sapiens | |||
13. | ALA5173613 | 2c; KR-25210 | Activity | 0 | ALA5146850 | Active | rhinovirus B14 | |||||
14. | ALA5173613 | 2c; KR-25210 | CC50 | > | 30 | uM | ALA5146847 | nM | Homo sapiens | |||
15. | ALA5173613 | 2c; KR-25210 | IC50 | = | 1.7 | uM | ALA5146846 | 5.77 | nM | |||
16. | ALA5173613 | 2c; KR-25210 | Activity | 0 | ALA5146844 | NA | rhinovirus B14 | |||||
17. | ALA5173613 | 2c; KR-25210 | Activity | 0 | ALA5146843 | Dde | rhinovirus B14 | |||||
18. | ALA5173613 | 2c; KR-25210 | EC50 | = | 1.67 | uM | ALA5146842 | 5.78 | nM | Poliovirus 3 | ||
19. | ALA5173613 | 2c; KR-25210 | EC50 | = | 19.77 | uM | ALA5146841 | 4.70 | nM | Coxsackievirus B1 | ||
20. | ALA5173613 | 2c; KR-25210 | EC50 | = | 1.7 | uM | ALA5146840 | 5.77 | nM | Rhinovirus B |