# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5174111 | GC-14 | CC50 | > | 100 | uM | ALA5154221 | nM | Chlorocebus sabaeus | |||
2. | ALA5174111 | GC-14 | EC50 | = | 0.4 | uM | ALA5154220 | 6.40 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
3. | ALA5174111 | GC-14 | IC50 | = | 0.4 | uM | ALA5154218 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
4. | ALA5174111 | GC-14 | INH | = | 94 | % | ALA5154217 | % | Severe acute respiratory syndrome coronavirus 2 | |||
5. | ALA5174111 | GC-14 | Kinetic_solubility | = | 0.004 | mg/ml | ALA5106639 | ug.mL-1 | ||||
6. | ALA5174111 | GC-14 | F | = | 72 | % | ALA5106638 | % | ||||
7. | ALA5174111 | GC-14 | MRT | = | 2.45 | hr | ALA5106637 | hr | ||||
8. | ALA5174111 | GC-14 | AUC | = | 230 | hr.ng/ml | ALA5106636 | ng.hr.mL-1 | ||||
9. | ALA5174111 | GC-14 | AUCt | = | 235 | hr.ng/ml | ALA5106635 | ng.hr.mL-1 | ||||
10. | ALA5174111 | GC-14 | Cmax | = | 74.6 | ng/ml | ALA5106634 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
11. | ALA5174111 | GC-14 | Tmax | = | 0.5 | hr | ALA5106633 | hr | ||||
12. | ALA5174111 | GC-14 | CL | = | 3140 | ml/hr/kg | ALA5106632 | mL.min-1.kg-1 | ||||
13. | ALA5174111 | GC-14 | MRT | = | 0.4 | hr | ALA5106631 | hr | ||||
14. | ALA5174111 | GC-14 | t1/2 | = | 1.73 | hr | ALA5106630 | hr | ||||
15. | ALA5174111 | GC-14 | AUC | = | 637 | hr.ng/ml | ALA5106629 | ng.hr.mL-1 | ||||
16. | ALA5174111 | GC-14 | AUCt | = | 627 | hr.ng/ml | ALA5106628 | ng.hr.mL-1 | ||||
17. | ALA5174111 | GC-14 | C0 | = | 1760 | ng/ml | ALA5106627 | ng/ml | ||||
18. | ALA5174111 | GC-14 | Cmax | = | 1310 | ng/ml | ALA5106626 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA5174111 | GC-14 | Tmax | = | 0.08 | hr | ALA5106625 | hr | ||||
20. | ALA5174111 | GC-14 | t1/2 | = | 0.36 | hr | ALA5106624 | hr |