| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5174279 | 25 | F | = | 54 | % | ALA5100342 | % | ||||
| 2. | ALA5174279 | 25 | AUC | = | 33587 | nM.hr | ALA5100341 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 3. | ALA5174279 | 25 | Cmax | = | 6173 | nM | ALA5100340 | nM | ||||
| 4. | ALA5174279 | 25 | t1/2 | = | 5.3 | hr | ALA5100339 | hr | ||||
| 5. | ALA5174279 | 25 | Vdss | = | 0.35 | L/Kg | ALA5100338 | L.kg-1 | ||||
| 6. | ALA5174279 | 25 | QH | = | 3.3 | % | ALA5100337 | % | ||||
| 7. | ALA5174279 | 25 | IC50 | = | 3.9 | uM | ALA5100336 | 5.41 | nM | Homo sapiens | ||
| 8. | ALA5174279 | 25 | solubility | > | 400 | ug ml-1 | ALA5100335 | ug.mL-1 | ||||
| 9. | ALA5174279 | 25 | solubility | = | 118 | ug ml-1 | ALA5100334 | ug.mL-1 | ||||
| 10. | ALA5174279 | 25 | CLH | = | 0.5 | L/hr/kg | ALA5100333 | mL.min-1.kg-1 | ||||
| 11. | ALA5174279 | 25 | Papp | = | 5.7 | 10^-6 cm/s | ALA5100332 | 10^-6 cm/s | ||||
| 12. | ALA5174279 | 25 | IC50 | = | 1741 | nM | ALA5100331 | 5.76 | nM | Homo sapiens | ||
| 13. | ALA5174279 | 25 | IC50 | = | 1449 | nM | ALA5100330 | 5.84 | nM | Homo sapiens | ||
| 14. | ALA5174279 | 25 | IC50 | = | 285 | nM | ALA5100329 | 6.54 | nM | Homo sapiens | ||
| 15. | ALA5174279 | 25 | IC50 | = | 155 | nM | ALA5100328 | 6.81 | nM | Homo sapiens | ||
| 16. | ALA5174279 | 25 | IC50 | = | 68 | nM | ALA5100327 | 7.17 | nM | Mus musculus | ||
| 17. | ALA5174279 | 25 | IC50 | = | 21 | nM | ALA5100325 | 7.68 | nM | Homo sapiens | ||
| 18. | ALA5174279 | 25 | IC50 | = | 0.6 | nM | ALA5100323 | 9.22 | nM | Homo sapiens |
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