| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5176075 | 3 | Activity | 0 | ALA5161543 | NA | Mus musculus | |||||
| 2. | ALA5176075 | 3 | INH | = | 89.54 | % | ALA5161542 | % | Rattus norvegicus | |||
| 3. | ALA5176075 | 3 | INH | > | 70 | % | ALA5161541 | % | Rattus norvegicus | |||
| 4. | ALA5176075 | 3 | INH | = | 48.58 | % | ALA5161540 | % | Rattus norvegicus | |||
| 5. | ALA5176075 | 3 | INH | = | 56.66 | % | ALA5161539 | % | Rattus norvegicus | |||
| 6. | ALA5176075 | 3 | Vd | = | 0.131 | L/Kg | ALA5161538 | L.kg-1 | ||||
| 7. | ALA5176075 | 3 | CL | = | 0.021 | L/Kg.hr | ALA5161537 | L/Kg.hr | ||||
| 8. | ALA5176075 | 3 | t1/2 | = | 6.2 | hr | ALA5161536 | hr | ||||
| 9. | ALA5176075 | 3 | Cmax | = | 2016.5 | ug/L | ALA5161535 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA5176075 | 3 | Tmax | = | 1.5 | hr | ALA5161534 | hr | ||||
| 11. | ALA5176075 | 3 | IC50 | = | 12.53 | uM | ALA5161533 | 4.90 | nM | Homo sapiens | ||
| 12. | ALA5176075 | 3 | IC50 | = | 787.9 | nM | ALA5161532 | 6.10 | nM | Homo sapiens | ||
| 13. | ALA5176075 | 3 | IC50 | = | 108.1 | nM | ALA5161531 | 6.97 | nM | Homo sapiens | ||
| 14. | ALA5176075 | 3 | 2TT | > | 128 | ug ml-1 | ALA5161530 | ug ml-1 | Homo sapiens | |||
| 15. | ALA5176075 | 3 | EC | > | 128 | ug ml-1 | ALA5161529 | ug ml-1 | Homo sapiens | |||
| 16. | ALA5176075 | 3 | EC | = | 48.78 | uM | ALA5161528 | uM | Homo sapiens | |||
| 17. | ALA5176075 | 3 | AUC | = | 14176.2 | hr.ug/L | ALA5161527 | ng.hr.mL-1 | ||||
| 18. | ALA5176075 | 3 | AUC | = | 15536.1 | hr.ug/L | ALA5161526 | ng.hr.mL-1 | ||||
| 19. | ALA5176075 | 3 | INH | 0 | ALA5161524 | Active | % | Rattus norvegicus |
The page will load shortly, Thanks for your patience!