# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5176564 | 16b; [(R'S)-EHPMPG] | Selectivity Index | > | 185 | ALA5124945 | ||||||
2. | ALA5176564 | 16b; [(R'S)-EHPMPG] | Selectivity Index | > | 322 | ALA5124944 | ||||||
3. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC50 | = | 0.54 | uM | ALA5124943 | 6.27 | nM | Hepatitis B virus | ||
4. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC90 | = | 1.8 | uM | ALA5124943 | uM | Hepatitis B virus | |||
5. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC50 | = | 0.31 | uM | ALA5124942 | 6.51 | nM | Hepatitis B virus | ||
6. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC90 | = | 0.8 | uM | ALA5124942 | uM | Hepatitis B virus | |||
7. | ALA5176564 | 16b; [(R'S)-EHPMPG] | CC50 | > | 100 | uM | ALA5124941 | nM | Homo sapiens | |||
8. | ALA5176564 | 16b; [(R'S)-EHPMPG] | CC50 | > | 100 | uM | ALA5124940 | nM | Homo sapiens | |||
9. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC90 | = | 0.83 | uM | ALA5124938 | uM | Hepatitis B virus | |||
10. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC50 | = | 0.37 | uM | ALA5124938 | 6.43 | nM | Hepatitis B virus | ||
11. | ALA5176564 | 16b; [(R'S)-EHPMPG] | Ratio CC50/EC50 | > | 287 | ALA5124937 | ||||||
12. | ALA5176564 | 16b; [(R'S)-EHPMPG] | Ratio CC50/EC50 | > | 97 | ALA5124936 | ||||||
13. | ALA5176564 | 16b; [(R'S)-EHPMPG] | CC50 | > | 364.18 | uM | ALA5124935 | nM | Homo sapiens | |||
14. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC50 | = | 1.28 | uM | ALA5124934 | 5.89 | nM | Human immunodeficiency virus 2 | ||
15. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC50 | = | 3.73 | uM | ALA5124933 | 5.43 | nM | Human immunodeficiency virus 1 | ||
16. | ALA5176564 | 16b; [(R'S)-EHPMPG] | Ratio CC50/EC50 | > | 1 | ALA5124932 | ||||||
17. | ALA5176564 | 16b; [(R'S)-EHPMPG] | CC50 | > | 150 | uM | ALA5124931 | nM | Homo sapiens | |||
18. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC90 | > | 150 | uM | ALA5124930 | uM | Human alphaherpesvirus 3 | |||
19. | ALA5176564 | 16b; [(R'S)-EHPMPG] | EC50 | = | 115.93 | uM | ALA5124930 | nM | Human alphaherpesvirus 3 | |||
20. | ALA5176564 | 16b; [(R'S)-EHPMPG] | Ratio CC50/EC50 | > | 10 | ALA5124929 |