# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5176874 | I-9 | IC50 | = | 4.15 | nM | ALA5127752 | 8.38 | nM | Homo sapiens | ||
2. | ALA5176874 | I-9 | IC50 | = | 13.5 | nM | ALA5127751 | 7.87 | nM | Homo sapiens | ||
3. | ALA5176874 | I-9 | IC50 | = | 0.25 | nM | ALA5127750 | 9.60 | nM | Homo sapiens | ||
4. | ALA5176874 | I-9 | TGI | = | 51.74 | % | ALA5123691 | % | Homo sapiens | |||
5. | ALA5176874 | I-9 | TGI | = | 31.73 | % | ALA5123690 | % | Homo sapiens | |||
6. | ALA5176874 | I-9 | Activity | 0 | ALA5123688 | Non-Toxic | ||||||
7. | ALA5176874 | I-9 | Activity | 0 | ALA5123687 | Non-Toxic | ||||||
8. | ALA5176874 | I-9 | Activity | 0 | ALA5123686 | Non-Toxic | ||||||
9. | ALA5176874 | I-9 | Activity | 0 | ALA5123685 | Non-Toxic | ||||||
10. | ALA5176874 | I-9 | Activity | 0 | ALA5123684 | Non-Toxic | ||||||
11. | ALA5176874 | I-9 | Activity | 0 | ALA5123683 | Non-Toxic | ||||||
12. | ALA5176874 | I-9 | Activity | = | 24.25 | g | ALA5123682 | g | ||||
13. | ALA5176874 | I-9 | Activity | = | 23 | g | ALA5123681 | g | ||||
14. | ALA5176874 | I-9 | Activity | = | 20.75 | g | ALA5123680 | g | ||||
15. | ALA5176874 | I-9 | Activity | 0 | ALA5123679 | Non-Toxic | ||||||
16. | ALA5176874 | I-9 | CL | = | 5440 | ml/hr/kg | ALA5123678 | mL.min-1.kg-1 | ||||
17. | ALA5176874 | I-9 | t1/2 | = | 1.73 | hr | ALA5123677 | hr | ||||
18. | ALA5176874 | I-9 | IC50 | = | 1369 | nM | ALA5123676 | 5.86 | nM | Homo sapiens | ||
19. | ALA5176874 | I-9 | IC50 | = | 371 | nM | ALA5123675 | 6.43 | nM | Homo sapiens | ||
20. | ALA5176874 | I-9 | IC50 | = | 140 | nM | ALA5123674 | 6.85 | nM | Homo sapiens |