| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5177284 | 10w | Drug uptake | = | 9140 | ng/g | ALA5136635 | ng/g | ||||
| 2. | ALA5177284 | 10w | Drug uptake | = | 3616 | ng/g | ALA5136634 | ng/g | ||||
| 3. | ALA5177284 | 10w | Activity | 0 | ALA5136633 | Active | Mus musculus | |||||
| 4. | ALA5177284 | 10w | Activity | 0 | ALA5136632 | Active | Mus musculus | |||||
| 5. | ALA5177284 | 10w | Activity | 0 | ALA5136631 | Active | Mus musculus | |||||
| 6. | ALA5177284 | 10w | Activity | 0 | ALA5136630 | Active | Mus musculus | |||||
| 7. | ALA5177284 | 10w | F | = | 15.05 | % | ALA5136629 | % | ||||
| 8. | ALA5177284 | 10w | Vd | = | 333.24 | L/Kg | ALA5136628 | L.kg-1 | ||||
| 9. | ALA5177284 | 10w | Vd | = | 43.94 | L/Kg | ALA5136627 | L.kg-1 | ||||
| 10. | ALA5177284 | 10w | AUCt | = | 150.88 | ug/L.hr | ALA5136626 | ng.hr.mL-1 | ||||
| 11. | ALA5177284 | 10w | AUCt | = | 1002.81 | ug/L.hr | ALA5136625 | ng.hr.mL-1 | ||||
| 12. | ALA5177284 | 10w | CL | = | 67.78 | L/hr/kg | ALA5136624 | mL.min-1.kg-1 | ||||
| 13. | ALA5177284 | 10w | beta t1/2 | = | 3.62 | hr | ALA5136623 | hr | ||||
| 14. | ALA5177284 | 10w | beta t1/2 | = | 3.9 | hr | ALA5136622 | hr | ||||
| 15. | ALA5177284 | 10w | Cmax | = | 68.07 | ug/L | ALA5136621 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 16. | ALA5177284 | 10w | Cmax | = | 958.55 | ug/L | ALA5136620 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA5177284 | 10w | Ratio | = | 260 | ALA5136619 | ||||||
| 18. | ALA5177284 | 10w | Kd | = | 670 | nM | ALA5136618 | 6.17 | nM | Homo sapiens | ||
| 19. | ALA5177284 | 10w | Kd | = | 2300 | nM | ALA5136617 | 5.64 | nM | Homo sapiens | ||
| 20. | ALA5177284 | 10w | Kd | = | 74.5 | nM | ALA5136616 | 7.13 | nM | Homo sapiens |
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