# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5177354 | 33 | F | = | 46 | % | ALA5139001 | % | ||||
2. | ALA5177354 | 33 | AUC | = | 762 | nM.hr | ALA5139000 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
3. | ALA5177354 | 33 | t1/2 | = | 1.2 | hr | ALA5138999 | hr | ||||
4. | ALA5177354 | 33 | Vdss | = | 4.4 | L/Kg | ALA5138998 | L.kg-1 | ||||
5. | ALA5177354 | 33 | CL | = | 52 | ml/min.kg | ALA5138997 | mL.min-1.kg-1 | ||||
6. | ALA5177354 | 33 | ERH | = | 54 | % | ALA5138996 | % | ||||
7. | ALA5177354 | 33 | ERH | = | 67 | % | ALA5138995 | % | ||||
8. | ALA5177354 | 33 | ERH | = | 27 | % | ALA5138994 | % | ||||
9. | ALA5177354 | 33 | Ct | = | 553 | pmol/g | ALA5138993 | pmol/g | ||||
10. | ALA5177354 | 33 | Ct | = | 1813 | pmol/g | ALA5138992 | pmol/g | ||||
11. | ALA5177354 | 33 | Ct | = | 616 | pmol/ml | ALA5138991 | pmol/ml | ||||
12. | ALA5177354 | 33 | Ct | = | 1640 | pmol/ml | ALA5138990 | pmol/ml | ||||
13. | ALA5177354 | 33 | BBR | = | 0.9 | ALA5138989 | ||||||
14. | ALA5177354 | 33 | BBR | = | 1.11 | ALA5138988 | ||||||
15. | ALA5177354 | 33 | IC50 | = | 28 | nM | ALA5138981 | 7.55 | nM | |||
16. | ALA5177354 | 33 | IC50 | = | 65 | nM | ALA5138980 | 7.19 | nM | Rattus norvegicus | ||
17. | ALA5177354 | 33 | IC50 | = | 48 | nM | ALA5138979 | 7.32 | nM | Rattus norvegicus | ||
18. | ALA5177354 | 33 | IC50 | = | 2878 | nM | ALA5138978 | 5.54 | nM | Homo sapiens |