# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5177475 | 5a; NN-390 | AUClast | = | 1.94 | hr.ng/ml | ALA5158398 | ng.hr.mL-1 | ||||
2. | ALA5177475 | 5a; NN-390 | t1/2 | = | 115.1 | min | ALA5158392 | hr | ||||
3. | ALA5177475 | 5a; NN-390 | log Pe | = | -4.74 | ALA5158391 | ||||||
4. | ALA5177475 | 5a; NN-390 | log Pe | = | -4.97 | ALA5158390 | ||||||
5. | ALA5177475 | 5a; NN-390 | Cmax | = | 1.94 | ng/ml | ALA5158389 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
6. | ALA5177475 | 5a; NN-390 | Activity | 0 | ALA5158388 | NA | ||||||
7. | ALA5177475 | 5a; NN-390 | Activity | 0 | ALA5158387 | Active | ||||||
8. | ALA5177475 | 5a; NN-390 | Activity | 0 | ALA5158386 | NA | ||||||
9. | ALA5177475 | 5a; NN-390 | Activity | 0 | ALA5158385 | Active | ||||||
10. | ALA5177475 | 5a; NN-390 | Ratio IC50 | = | 2.5 | ALA5158384 | ||||||
11. | ALA5177475 | 5a; NN-390 | Ratio IC50 | = | 40 | ALA5158383 | ||||||
12. | ALA5177475 | 5a; NN-390 | Ratio IC50 | = | 45 | ALA5158382 | ||||||
13. | ALA5177475 | 5a; NN-390 | IC50 | = | 0.13 | uM | ALA5158381 | 6.89 | nM | |||
14. | ALA5177475 | 5a; NN-390 | Activity | = | 39 | % | ALA5158380 | % | Homo sapiens | |||
15. | ALA5177475 | 5a; NN-390 | Activity | = | 23.4 | % | ALA5158379 | % | Homo sapiens | |||
16. | ALA5177475 | 5a; NN-390 | Activity | = | 3.59 | % | ALA5158378 | % | Homo sapiens | |||
17. | ALA5177475 | 5a; NN-390 | Activity | = | 32.87 | % | ALA5158377 | % | Homo sapiens | |||
18. | ALA5177475 | 5a; NN-390 | Activity | = | 10.88 | % | ALA5158376 | % | Homo sapiens | |||
19. | ALA5177475 | 5a; NN-390 | Activity | = | 3.32 | % | ALA5158375 | % | Homo sapiens | |||
20. | ALA5177475 | 5a; NN-390 | Activity | = | 56.27 | % | ALA5158374 | % | Homo sapiens |