| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5177656 | 34 | Kinetic_solubility | = | 86 | uM | ALA5165217 | nM | ||||
| 2. | ALA5177656 | 34 | Kinetic_solubility | = | 80 | uM | ALA5165217 | nM | ||||
| 3. | ALA5177656 | 34 | F | = | 73 | % | ALA5165216 | % | ||||
| 4. | ALA5177656 | 34 | F | = | 28 | % | ALA5165216 | % | ||||
| 5. | ALA5177656 | 34 | t1/2 | = | 1.2 | hr | ALA5165215 | hr | ||||
| 6. | ALA5177656 | 34 | t1/2 | = | 1.2 | hr | ALA5165215 | hr | ||||
| 7. | ALA5177656 | 34 | AUC | = | 1712 | hr.ng/ml | ALA5165214 | ng.hr.mL-1 | ||||
| 8. | ALA5177656 | 34 | AUC | = | 397 | hr.ng/ml | ALA5165214 | ng.hr.mL-1 | ||||
| 9. | ALA5177656 | 34 | Cmax | = | 2013 | ng/ml | ALA5165213 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA5177656 | 34 | Cmax | = | 279 | ng/ml | ALA5165213 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA5177656 | 34 | Vdss | = | 2.3 | L/Kg | ALA5165212 | L.kg-1 | ||||
| 12. | ALA5177656 | 34 | Vdss | = | 3.8 | L/Kg | ALA5165212 | L.kg-1 | ||||
| 13. | ALA5177656 | 34 | AUC | = | 707 | hr.ng/ml | ALA5165211 | ng.hr.mL-1 | ||||
| 14. | ALA5177656 | 34 | AUC | = | 429 | hr.ng/ml | ALA5165211 | ng.hr.mL-1 | ||||
| 15. | ALA5177656 | 34 | Selectivity ratio | = | 200 | ALA5165210 | ||||||
| 16. | ALA5177656 | 34 | Selectivity ratio | = | 200 | ALA5165210 | ||||||
| 17. | ALA5177656 | 34 | CLH | = | 31 | microL/min/mg | ALA5165209 | mL.min-1.g-1 | ||||
| 18. | ALA5177656 | 34 | CLH | = | 60 | microL/min/mg | ALA5165209 | mL.min-1.g-1 | ||||
| 19. | ALA5177656 | 34 | GI50 | = | 19 | nM | ALA5165208 | nM | Homo sapiens | |||
| 20. | ALA5177656 | 34 | GI50 | = | 26 | nM | ALA5165208 | nM | Homo sapiens |
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