# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5179476 | 16; HEC-866 | MTD | > | 500 | mg kg-1 | ALA5137202 | mg kg-1 | ||||
2. | ALA5179476 | 16; HEC-866 | Activity | 0 | ALA5137201 | Non-Toxic | ||||||
3. | ALA5179476 | 16; HEC-866 | Activity | 0 | ALA5137200 | Non-Toxic | ||||||
4. | ALA5179476 | 16; HEC-866 | IC50 | > | 30 | uM | ALA5137199 | nM | Homo sapiens | |||
5. | ALA5179476 | 16; HEC-866 | IC50 | > | 10 | uM | ALA5137198 | nM | Homo sapiens | |||
6. | ALA5179476 | 16; HEC-866 | IC50 | > | 10 | uM | ALA5137197 | nM | Homo sapiens | |||
7. | ALA5179476 | 16; HEC-866 | IC50 | > | 10 | uM | ALA5137196 | nM | Homo sapiens | |||
8. | ALA5179476 | 16; HEC-866 | IC50 | > | 10 | uM | ALA5137195 | nM | Homo sapiens | |||
9. | ALA5179476 | 16; HEC-866 | IC50 | > | 10 | uM | ALA5137194 | nM | Homo sapiens | |||
10. | ALA5179476 | 16; HEC-866 | CLH | = | 77 | ml/min.Kg | ALA5137193 | mL.min-1.kg-1 | ||||
11. | ALA5179476 | 16; HEC-866 | CLH | = | 24.2 | ml/min.Kg | ALA5137192 | mL.min-1.kg-1 | ||||
12. | ALA5179476 | 16; HEC-866 | CLH | = | 11.7 | ml/min.Kg | ALA5137191 | mL.min-1.kg-1 | ||||
13. | ALA5179476 | 16; HEC-866 | CLH | = | 48.6 | ml/min.Kg | ALA5137190 | mL.min-1.kg-1 | ||||
14. | ALA5179476 | 16; HEC-866 | CLH | = | 16.7 | ml/min.Kg | ALA5137189 | mL.min-1.kg-1 | ||||
15. | ALA5179476 | 16; HEC-866 | t1/2 | = | 70.9 | min | ALA5137188 | hr | ||||
16. | ALA5179476 | 16; HEC-866 | t1/2 | = | 102.5 | min | ALA5137187 | hr | ||||
17. | ALA5179476 | 16; HEC-866 | t1/2 | = | 295.7 | min | ALA5137186 | hr | ||||
18. | ALA5179476 | 16; HEC-866 | t1/2 | = | 41.7 | min | ALA5137185 | hr | ||||
19. | ALA5179476 | 16; HEC-866 | t1/2 | = | 104.1 | min | ALA5137184 | hr | ||||
20. | ALA5179476 | 16; HEC-866 | Activity | 0 | ALA5137182 | Dde | Rattus norvegicus |