# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5179988 | 3 | ED90 | = | 5.3 | mg kg-1 | ALA5160139 | mg kg-1 | Plasmodium falciparum | |||
2. | ALA5179988 | 3 | AUC | = | 57.3 | ug.hr/ml | ALA5160093 | ng.hr.mL-1 | ||||
3. | ALA5179988 | 3 | AUC | = | 6.2 | ug.hr/ml | ALA5160092 | ng.hr.mL-1 | ||||
4. | ALA5179988 | 3 | AUC | = | 87.1 | ug.hr/ml | ALA5160089 | ng.hr.mL-1 | ||||
5. | ALA5179988 | 3 | AUC | = | 8.4 | ug.hr/ml | ALA5160088 | ng.hr.mL-1 | ||||
6. | ALA5179988 | 3 | Time | > | 60 | day | ALA5160079 | hr | Plasmodium falciparum | |||
7. | ALA5179988 | 3 | Time | = | 0 | day | ALA5160078 | hr | Plasmodium falciparum | |||
8. | ALA5179988 | 3 | Activity | > | 99.9 | % | ALA5160070 | % | Plasmodium falciparum | |||
9. | ALA5179988 | 3 | Kd | = | 0.01 | uM | ALA5160058 | 8.00 | nM | Homo sapiens | ||
10. | ALA5179988 | 3 | Kd | = | 0.1 | uM | ALA5160046 | 7.00 | nM | Homo sapiens | ||
11. | ALA5179988 | 3 | Kd | = | 0.2 | uM | ALA5160045 | 6.70 | nM | Homo sapiens | ||
12. | ALA5179988 | 3 | Kd | = | 0.2 | uM | ALA5160044 | 6.70 | nM | Homo sapiens | ||
13. | ALA5179988 | 3 | Kd | = | 1.5 | uM | ALA5160043 | 5.82 | nM | Homo sapiens | ||
14. | ALA5179988 | 3 | Kd | = | 0.1 | uM | ALA5160042 | 7.00 | nM | Homo sapiens | ||
15. | ALA5179988 | 3 | Kd | = | 0.2 | uM | ALA5160041 | 6.70 | nM | Homo sapiens | ||
16. | ALA5179988 | 3 | IC50 | = | 22 | uM | ALA5160040 | 4.66 | nM | Homo sapiens | ||
17. | ALA5179988 | 3 | CLH | < | 25 | microL/min/mg | ALA5160039 | mL.min-1.g-1 | ||||
18. | ALA5179988 | 3 | CLH | = | 32 | microL/min/mg | ALA5160038 | mL.min-1.g-1 | ||||
19. | ALA5179988 | 3 | CLH | < | 25 | microL/min/mg | ALA5160037 | mL.min-1.g-1 | ||||
20. | ALA5179988 | 3 | Drug degradation | = | 7.8 | % | ALA5160036 | % |