# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5180874 | 2; JBD0131 | Drug uptake | 0 | ALA5117298 | Active | ||||||
2. | ALA5180874 | 2; JBD0131 | Drug uptake | 0 | ALA5117297 | Active | ||||||
3. | ALA5180874 | 2; JBD0131 | Drug uptake | 0 | ALA5117296 | Active | ||||||
4. | ALA5180874 | 2; JBD0131 | Drug uptake | 0 | ALA5117295 | Active | ||||||
5. | ALA5180874 | 2; JBD0131 | Activity | 0 | ALA5117294 | Non-Toxic | ||||||
6. | ALA5180874 | 2; JBD0131 | F | = | 26.4 | % | ALA5117293 | % | ||||
7. | ALA5180874 | 2; JBD0131 | AUClast | = | 1910 | ng.hr | ALA5117292 | ng.hr | ||||
8. | ALA5180874 | 2; JBD0131 | Cmax | = | 141 | nM | ALA5117291 | nM | ||||
9. | ALA5180874 | 2; JBD0131 | t1/2 | = | 6.03 | hr | ALA5117290 | hr | ||||
10. | ALA5180874 | 2; JBD0131 | Vd | = | 4.52 | L/Kg | ALA5117289 | L.kg-1 | ||||
11. | ALA5180874 | 2; JBD0131 | CL | = | 12 | ml/min.kg | ALA5117288 | mL.min-1.kg-1 | ||||
12. | ALA5180874 | 2; JBD0131 | F | = | 66.9 | % | ALA5117287 | % | ||||
13. | ALA5180874 | 2; JBD0131 | AUClast | = | 4520 | ng.hr | ALA5117286 | ng.hr | ||||
14. | ALA5180874 | 2; JBD0131 | Cmax | = | 526 | nM | ALA5117285 | nM | ||||
15. | ALA5180874 | 2; JBD0131 | t1/2 | = | 2.79 | hr | ALA5117284 | hr | ||||
16. | ALA5180874 | 2; JBD0131 | Vd | = | 5.56 | L/Kg | ALA5117283 | L.kg-1 | ||||
17. | ALA5180874 | 2; JBD0131 | CL | = | 24.6 | ml/min.kg | ALA5117282 | mL.min-1.kg-1 | ||||
18. | ALA5180874 | 2; JBD0131 | IC50 | > | 13.3 | uM | ALA5117281 | nM | Homo sapiens | |||
19. | ALA5180874 | 2; JBD0131 | IC50 | > | 13.3 | uM | ALA5117280 | nM | Homo sapiens | |||
20. | ALA5180874 | 2; JBD0131 | IC50 | > | 13.3 | uM | ALA5117279 | nM | Homo sapiens |