# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5180987 | 4 | Activity | 0 | ALA5161543 | NA | Mus musculus | |||||
2. | ALA5180987 | 4 | INH | = | 93.12 | % | ALA5161542 | % | Rattus norvegicus | |||
3. | ALA5180987 | 4 | INH | > | 70 | % | ALA5161541 | % | Rattus norvegicus | |||
4. | ALA5180987 | 4 | INH | < | 15 | % | ALA5161540 | % | Rattus norvegicus | |||
5. | ALA5180987 | 4 | INH | = | 77.78 | % | ALA5161539 | % | Rattus norvegicus | |||
6. | ALA5180987 | 4 | Vd | = | 0.058 | L/Kg | ALA5161538 | L.kg-1 | ||||
7. | ALA5180987 | 4 | CL | = | 0.031 | L/Kg.hr | ALA5161537 | L/Kg.hr | ||||
8. | ALA5180987 | 4 | t1/2 | = | 6.1 | hr | ALA5161536 | hr | ||||
9. | ALA5180987 | 4 | Cmax | = | 2041 | ug/L | ALA5161535 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA5180987 | 4 | Tmax | = | 2 | hr | ALA5161534 | hr | ||||
11. | ALA5180987 | 4 | IC50 | = | 12.17 | uM | ALA5161533 | 4.92 | nM | Homo sapiens | ||
12. | ALA5180987 | 4 | IC50 | = | 724.7 | nM | ALA5161532 | 6.14 | nM | Homo sapiens | ||
13. | ALA5180987 | 4 | IC50 | = | 141.08 | nM | ALA5161531 | 6.85 | nM | Homo sapiens | ||
14. | ALA5180987 | 4 | 2TT | > | 128 | ug ml-1 | ALA5161530 | ug ml-1 | Homo sapiens | |||
15. | ALA5180987 | 4 | EC | > | 128 | ug ml-1 | ALA5161529 | ug ml-1 | Homo sapiens | |||
16. | ALA5180987 | 4 | EC | = | 40.83 | uM | ALA5161528 | uM | Homo sapiens | |||
17. | ALA5180987 | 4 | AUC | = | 17623.6 | hr.ug/L | ALA5161527 | ng.hr.mL-1 | ||||
18. | ALA5180987 | 4 | AUC | = | 19053.2 | hr.ug/L | ALA5161526 | ng.hr.mL-1 |