# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5181350 | 18 | INH | 0 | ALA5130524 | NA | % | Homo sapiens | ||||
2. | ALA5181350 | 18 | F | = | 7.4 | % | ALA5130520 | % | ||||
3. | ALA5181350 | 18 | CL | = | 20 | ml/min.kg | ALA5130519 | mL.min-1.kg-1 | ||||
4. | ALA5181350 | 18 | IC50 | = | 8.8 | uM | ALA5130518 | 5.06 | nM | Homo sapiens | ||
5. | ALA5181350 | 18 | IC50 | > | 30 | uM | ALA5130517 | nM | Homo sapiens | |||
6. | ALA5181350 | 18 | IC50 | > | 30 | uM | ALA5130516 | nM | Homo sapiens | |||
7. | ALA5181350 | 18 | IC50 | > | 30 | uM | ALA5130515 | nM | Homo sapiens | |||
8. | ALA5181350 | 18 | IC50 | = | 23 | uM | ALA5130514 | 4.64 | nM | Homo sapiens | ||
9. | ALA5181350 | 18 | Papp | = | 1.3 | 10^-6 cm/s | ALA5130513 | 10^-6 cm/s | ||||
10. | ALA5181350 | 18 | CLH | < | 1 | uL/min | ALA5130512 | uL/min | ||||
11. | ALA5181350 | 18 | CLH | < | 1 | uL/min | ALA5130511 | uL/min | ||||
12. | ALA5181350 | 18 | CLH | < | 3 | uL/min | ALA5130510 | uL/min | ||||
13. | ALA5181350 | 18 | Therm_solubility | = | 880 | uM | ALA5130509 | nM | ||||
14. | ALA5181350 | 18 | logD | = | 0.7 | ALA5130508 | ||||||
15. | ALA5181350 | 18 | FC | = | 1.03 | ALA5130504 | Homo sapiens | |||||
16. | ALA5181350 | 18 | Ratio IC50 | = | 214 | ALA5130503 | ||||||
17. | ALA5181350 | 18 | IC50 | = | 0.77 | uM | ALA5130502 | 6.11 | nM | Homo sapiens | ||
18. | ALA5181350 | 18 | IC50 | = | 3.1 | uM | ALA5130501 | 5.51 | nM | Homo sapiens | ||
19. | ALA5181350 | 18 | IC50 | > | 30 | uM | ALA5130500 | nM | Homo sapiens | |||
20. | ALA5181350 | 18 | IC50 | = | 3.6 | nM | ALA5130499 | 8.44 | nM | Homo sapiens |