# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5181454 | 2g | Ratio | = | 0.39 | ALA5152889 | ||||||
2. | ALA5181454 | 2g | K(p,uu,brain) | = | 0.04 | ALA5152888 | ||||||
3. | ALA5181454 | 2g | Drug uptake(free) | = | 0.7 | nM | ALA5152887 | nM | ||||
4. | ALA5181454 | 2g | Cp(f) | = | 17 | nM | ALA5152886 | nM | ||||
5. | ALA5181454 | 2g | Ct | = | 17 | ng/g | ALA5152885 | ng/g | ||||
6. | ALA5181454 | 2g | Cp | = | 76 | ng/ml | ALA5152884 | ng/ml | ||||
7. | ALA5181454 | 2g | Fu | = | 0.022 | ALA5152883 | ||||||
8. | ALA5181454 | 2g | Fu | = | 0.11 | ALA5152882 | ||||||
9. | ALA5181454 | 2g | IC50 | = | 1.8 | nM | ALA5152881 | 8.74 | nM | Mus musculus | ||
10. | ALA5181454 | 2g | CLH | = | 52 | microL/min/mg | ALA5152880 | mL.min-1.g-1 | ||||
11. | ALA5181454 | 2g | CLH | = | 33 | microL/min/mg | ALA5152879 | mL.min-1.g-1 | ||||
12. | ALA5181454 | 2g | Kinetic_solubility | = | 34 | ug ml-1 | ALA5152878 | ug.mL-1 | ||||
13. | ALA5181454 | 2g | logD | = | 2.9 | ALA5152877 | ||||||
14. | ALA5181454 | 2g | Ratio | = | 17 | ALA5152876 | ||||||
15. | ALA5181454 | 2g | IC50 | = | 3.6 | nM | ALA5152875 | 8.44 | nM | Homo sapiens |