| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5181639 | 3, Diastereomer | EC50 | = | 6.5 | uM | ALA5141598 | 5.19 | nM | Homo sapiens | ||
| 2. | ALA5181639 | 3, Diastereomer | EC50 | = | 6.2 | uM | ALA5141597 | 5.21 | nM | |||
| 3. | ALA5181639 | 3, Diastereomer | F | = | 62 | % | ALA5141592 | % | ||||
| 4. | ALA5181639 | 3, Diastereomer | PPB | = | 99.9 | % | ALA5141591 | % | ||||
| 5. | ALA5181639 | 3, Diastereomer | MRT | = | 2.3 | hr | ALA5141590 | hr | ||||
| 6. | ALA5181639 | 3, Diastereomer | CL | = | 2.5 | ml/min.kg | ALA5141589 | mL.min-1.kg-1 | ||||
| 7. | ALA5181639 | 3, Diastereomer | solubility | = | 36 | uM | ALA5141588 | nM | ||||
| 8. | ALA5181639 | 3, Diastereomer | solubility | = | 196 | uM | ALA5141587 | nM | ||||
| 9. | ALA5181639 | 3, Diastereomer | EC50 | = | 11.7 | uM | ALA5141586 | 4.93 | nM | Homo sapiens | ||
| 10. | ALA5181639 | 3, Diastereomer | Papp | = | 22 | 10^-6 cm/s | ALA5141585 | 10^-6 cm/s | ||||
| 11. | ALA5181639 | 3, Diastereomer | solubility | = | 157 | uM | ALA5141584 | nM | ||||
| 12. | ALA5181639 | 3, Diastereomer | EC50 | = | 1 | uM | ALA5141583 | 6.00 | nM | Homo sapiens | ||
| 13. | ALA5181639 | 3, Diastereomer | EC50 | = | 95 | uM | ALA5141582 | 4.02 | nM | Homo sapiens | ||
| 14. | ALA5181639 | 3, Diastereomer | Vd | = | 0.33 | L/Kg | ALA5141581 | L.kg-1 |
The page will load shortly, Thanks for your patience!