# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5181786 | 6 | F | = | 40 | % | ALA5126306 | % | ||||
2. | ALA5181786 | 6 | Vdss | = | 2.4 | L/Kg | ALA5126305 | L.kg-1 | ||||
3. | ALA5181786 | 6 | CL | = | 2.7 | ml/min.kg | ALA5126304 | mL.min-1.kg-1 | ||||
4. | ALA5181786 | 6 | AUC | = | 40 | uM.hr | ALA5126303 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
5. | ALA5181786 | 6 | Cmax | = | 5 | uM | ALA5126302 | nM | ||||
6. | ALA5181786 | 6 | Ratio IC50 | = | 208 | ALA5126295 | ||||||
7. | ALA5181786 | 6 | Ratio IC50 | = | 123 | ALA5126294 | ||||||
8. | ALA5181786 | 6 | IC50 | = | 2500 | nM | ALA5126293 | 5.60 | nM | Homo sapiens | ||
9. | ALA5181786 | 6 | IC50 | = | 2660 | nM | ALA5126292 | 5.58 | nM | Homo sapiens | ||
10. | ALA5181786 | 6 | IC50 | = | 48 | nM | ALA5126289 | 7.32 | nM | Mus musculus | ||
11. | ALA5181786 | 6 | IC50 | = | 6.9 | nM | ALA5126288 | 8.16 | nM | Homo sapiens |