# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5182699 | 12h | INH | = | 33 | % | ALA5149725 | % | Rattus norvegicus | |||
2. | ALA5182699 | 12h | INH | 0 | ALA5149724 | Active | % | Rattus norvegicus | ||||
3. | ALA5182699 | 12h | PPB | > | 97 | % | ALA5149723 | % | ||||
4. | ALA5182699 | 12h | PPB | > | 97 | % | ALA5149722 | % | ||||
5. | ALA5182699 | 12h | F | = | 25.45 | % | ALA5149721 | % | ||||
6. | ALA5182699 | 12h | AUC | = | 17.2 | uM.hr/ml | ALA5149720 | uM.hr/ml | ||||
7. | ALA5182699 | 12h | AUC | = | 13.64 | uM.hr/ml | ALA5149719 | uM.hr/ml | ||||
8. | ALA5182699 | 12h | t1/2 | = | 8.5 | hr | ALA5149718 | hr | ||||
9. | ALA5182699 | 12h | Cmax | = | 1.19 | ug ml-1 | ALA5149717 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA5182699 | 12h | Tmax | = | 6.67 | hr | ALA5149716 | hr | ||||
11. | ALA5182699 | 12h | Vdss | = | 1.83 | L/Kg | ALA5149715 | L.kg-1 | ||||
12. | ALA5182699 | 12h | CL | = | 0.27 | L/hr/kg | ALA5149714 | mL.min-1.kg-1 | ||||
13. | ALA5182699 | 12h | AUC | = | 30.63 | uM.hr/ml | ALA5149713 | uM.hr/ml | ||||
14. | ALA5182699 | 12h | AUC | = | 26.8 | uM.hr/ml | ALA5149712 | uM.hr/ml | ||||
15. | ALA5182699 | 12h | t1/2 | = | 6.59 | hr | ALA5149711 | hr | ||||
16. | ALA5182699 | 12h | Activity | 0 | ALA5149710 | Active | Rattus norvegicus | |||||
17. | ALA5182699 | 12h | Activity | 0 | ALA5149709 | Active | Rattus norvegicus | |||||
18. | ALA5182699 | 12h | FC | = | 1.3 | ALA5149708 | Rattus norvegicus | |||||
19. | ALA5182699 | 12h | delta(V1/2) | = | 7.5 | mV | ALA5149707 | mV | Rattus norvegicus | |||
20. | ALA5182699 | 12h | FC | = | 1.5 | ALA5149706 | Rattus norvegicus |