# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5183632 | CsO | Ki | = | 2.3 | uM | ALA5151442 | 5.64 | nM | Homo sapiens | ||
2. | ALA5183632 | CsO | Ratio | = | 5 | ALA5151441 | ||||||
3. | ALA5183632 | CsO | BPR | = | 0.62 | ALA5151440 | ||||||
4. | ALA5183632 | CsO | F | = | 12 | % | ALA5151439 | % | ||||
5. | ALA5183632 | CsO | t1/2 | = | 4.8 | hr | ALA5151438 | hr | ||||
6. | ALA5183632 | CsO | Vdss | = | 4 | L/Kg | ALA5151437 | L.kg-1 | ||||
7. | ALA5183632 | CsO | CL | = | 98 | ml/min.kg | ALA5151436 | mL.min-1.kg-1 | ||||
8. | ALA5183632 | CsO | AUC | = | 8500 | ng.hr/ml | ALA5151435 | ng.hr.mL-1 | ||||
9. | ALA5183632 | CsO | t1/2 | = | 3.1 | hr | ALA5151434 | hr | ||||
10. | ALA5183632 | CsO | Vz | = | 22.2 | L/Kg | ALA5151433 | L.kg-1 | ||||
11. | ALA5183632 | CsO | CL | = | 82 | ml/min.kg | ALA5151432 | mL.min-1.kg-1 | ||||
12. | ALA5183632 | CsO | Cmax | = | 1600 | ng/ml | ALA5151431 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
13. | ALA5183632 | CsO | AUC | = | 4080 | ng.hr/ml | ALA5151430 | ng.hr.mL-1 | ||||
14. | ALA5183632 | CsO | Tmax | = | 0.8 | hr | ALA5151429 | hr | ||||
15. | ALA5183632 | CsO | Drug recovery | = | 123 | % | ALA5151427 | % | ||||
16. | ALA5183632 | CsO | permeability | = | 0.69 | 10^-6 cm/s | ALA5151426 | 10^-6 cm/s | ||||
17. | ALA5183632 | CsO | Ratio | = | 10 | ALA5151425 | ||||||
18. | ALA5183632 | CsO | Drug recovery | = | 82 | % | ALA5151424 | % | ||||
19. | ALA5183632 | CsO | permeability | = | 2.88 | 10^-6 cm/s | ALA5151423 | 10^-6 cm/s | ||||
20. | ALA5183632 | CsO | Drug recovery | = | 82 | % | ALA5151422 | % |