Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA5183719	46	K(p,uu,brain)	=	0.54		ALA5166411
2.	ALA5183719	46	Kp	=	0.98		ALA5166410
3.	ALA5183719	46	Fu	=	2	%	ALA5166409
4.	ALA5183719	46	Fu	=	4	%	ALA5166408
5.	ALA5183719	46	AUC/dose	=	480	ng.hr/ml.mg	ALA5166407		ng.hr/ml.mg
6.	ALA5183719	46	AUC/dose	=	200	ng.hr/ml.mg	ALA5166406		ng.hr/ml.mg
7.	ALA5183719	46	F	=	57	%	ALA5166405		%
8.	ALA5183719	46	AUC/dose	=	490	ng.hr/ml.mg	ALA5166404		ng.hr/ml.mg
9.	ALA5183719	46	t1/2	=	2.9	hr	ALA5166403		hr
10.	ALA5183719	46	AUC/dose	=	860	ng.hr/ml.mg	ALA5166402		ng.hr/ml.mg
11.	ALA5183719	46	Vdss	=	3.6	L/Kg	ALA5166401		L.kg-1
12.	ALA5183719	46	CL	=	17	uL/min/kg	ALA5166400		mL.min-1.kg-1
13.	ALA5183719	46	CLH	=	10	uL/min	ALA5166399		uL/min
14.	ALA5183719	46	CLH	=	8	uL/min	ALA5166398		uL/min
15.	ALA5183719	46	CLH	<	14	microL/min/mg	ALA5166397		mL.min-1.g-1
16.	ALA5183719	46	CLH	<	14	microL/min/mg	ALA5166396		mL.min-1.g-1
17.	ALA5183719	46	logD	=	1.8		ALA5166395
18.	ALA5183719	46	EC50	=	0.79	uM	ALA5166394	6.10	nM	Mus musculus
19.	ALA5183719	46	EC50	=	0.71	uM	ALA5166393	6.15	nM	Homo sapiens
20.	ALA5183719	46	Ratio	=	0.7		ALA5166384