# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5184542 | 2h | Ct | = | 12.1 | uM | ALA5167075 | uM | ||||
2. | ALA5184542 | 2h | INH | = | 20 | % | ALA5167074 | % | Rattus norvegicus | |||
3. | ALA5184542 | 2h | Ratio | > | 2.5 | ALA5167073 | ||||||
4. | ALA5184542 | 2h | Drug uptake | = | 19 | % | ALA5167072 | % | ||||
5. | ALA5184542 | 2h | Drug uptake | = | 21 | % | ALA5167070 | % | ||||
6. | ALA5184542 | 2h | Ratio | = | 40 | ALA5167069 | ||||||
7. | ALA5184542 | 2h | Cmax | = | 3.18 | uM | ALA5167067 | nM | ||||
8. | ALA5184542 | 2h | Cmax | = | 0.06 | uM | ALA5167066 | nM | ||||
9. | ALA5184542 | 2h | PB | = | 99.9 | % | ALA5167063 | % | ||||
10. | ALA5184542 | 2h | PPB | > | 99.9 | % | ALA5167062 | % | ||||
11. | ALA5184542 | 2h | permeability | = | 2.5 | 10^-6 cm/s | ALA5167060 | 10^-6 cm/s | ||||
12. | ALA5184542 | 2h | solubility | = | 0.03 | mg/ml | ALA5167059 | ug.mL-1 | ||||
13. | ALA5184542 | 2h | IC50 | > | 10000 | nM | ALA5167058 | nM | Homo sapiens | |||
14. | ALA5184542 | 2h | IC50 | = | 16 | nM | ALA5167057 | 7.80 | nM | Homo sapiens | ||
15. | ALA5184542 | 2h | IC50 | = | 0.4 | nM | ALA5167056 | 9.40 | nM | Homo sapiens | ||
16. | ALA5184542 | 2h | t1/2 | > | 16 | hr | ALA5167055 | hr | Homo sapiens | |||
17. | ALA5184542 | 2h | IC50 | = | 0.3 | nM | ALA5167054 | 9.52 | nM | |||
18. | ALA5184542 | 2h | IC50 | = | 0.3 | nM | ALA5167053 | 9.52 | nM | Homo sapiens | ||
19. | ALA5184542 | 2h | t1/2 | < | 10 | min | ALA5167052 | hr |