# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5187481 | 1; Y1693 | Activity | = | 67 | % | ALA5126286 | % | Mus musculus | |||
2. | ALA5187481 | 1; Y1693 | Activity | = | 51.9 | % | ALA5126285 | % | Mus musculus | |||
3. | ALA5187481 | 1; Y1693 | Activity | = | 60.7 | % | ALA5126284 | % | Mus musculus | |||
4. | ALA5187481 | 1; Y1693 | Activity | 0 | ALA5126283 | Active | Mus musculus | |||||
5. | ALA5187481 | 1; Y1693 | t1/2 | = | 2 | hr | ALA5126282 | hr | ||||
6. | ALA5187481 | 1; Y1693 | Cmax | = | 48.1 | ng/ml | ALA5126281 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
7. | ALA5187481 | 1; Y1693 | AUCt | = | 223 | hr.ng/ml | ALA5126280 | ng.hr.mL-1 | ||||
8. | ALA5187481 | 1; Y1693 | Activity | = | 23.4 | % | ALA5126279 | % | Mus musculus | |||
9. | ALA5187481 | 1; Y1693 | F | = | 4.9 | % | ALA5126278 | % | ||||
10. | ALA5187481 | 1; Y1693 | CL | = | 18.6 | ml/min.kg | ALA5126277 | mL.min-1.kg-1 | ||||
11. | ALA5187481 | 1; Y1693 | t1/2 | = | 5.1 | hr | ALA5126276 | hr | ||||
12. | ALA5187481 | 1; Y1693 | AUCt | = | 2710 | hr.ng/ml | ALA5126275 | ng.hr.mL-1 | ||||
13. | ALA5187481 | 1; Y1693 | Activity | 0 | ALA5126274 | NA | ||||||
14. | ALA5187481 | 1; Y1693 | INH | 0 | ALA5126273 | Dde | % | |||||
15. | ALA5187481 | 1; Y1693 | INH | 0 | ALA5126272 | Dde | % | |||||
16. | ALA5187481 | 1; Y1693 | Kd | = | 5.03 | uM | ALA5126271 | 5.30 | nM | Homo sapiens | ||
17. | ALA5187481 | 1; Y1693 | INH | 0 | ALA5126270 | Active | % | |||||
18. | ALA5187481 | 1; Y1693 | INH | 0 | ALA5126269 | Active | % | |||||
19. | ALA5187481 | 1; Y1693 | INH | 0 | ALA5126268 | Active | % | |||||
20. | ALA5187481 | 1; Y1693 | INH | 0 | ALA5126267 | Active | % |