# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA652 | Flecainide | pKa | 9.3 | ALA2449009 | Basic pKa | ||||||
2. | ALA652 | Flecainide | Potency | 8.161 | uM | ALA2354254 | inconclusive | nM | Homo sapiens | |||
3. | ALA652 | Flecainide | Potency | 20.499 | uM | ALA2354221 | inconclusive | nM | Homo sapiens | |||
4. | ALA652 | Flecainide | Retention_time | = | 5.58 | min | ALA3062764 | min | Homo sapiens | |||
5. | ALA652 | Flecainide | Potency | 9.074 | uM | ALA1963912 | inconclusive | nM | ||||
6. | ALA652 | Flecainide | pKa | = | 9.28 | ALA3529441 | ||||||
7. | ALA652 | Flecainide | Hepatotoxicity (mechanism) | 0 | ALA3137740 | |||||||
8. | ALA652 | Flecainide | Hepatotoxicity (time to onset) | 0 | ALA3137739 | 2 days - 1 month | ||||||
9. | ALA652 | Flecainide | Hepatotoxicity (comment) | 0 | ALA3137738 | |||||||
10. | ALA652 | Flecainide | Hepatotoxicity (successful reintroduction) | 0 | ALA3137737 | |||||||
11. | ALA652 | Flecainide | Hepatotoxicity (animal toxicity known) | 0 | ALA3137736 | |||||||
12. | ALA652 | Flecainide | Hepatotoxicity (benign tumour) | = | 0 | ALA3137735 | references out of a total of 6 | |||||
13. | ALA652 | Flecainide | Hepatotoxicity (malignant tumour) | = | 0 | ALA3137734 | references out of a total of 6 | |||||
14. | ALA652 | Flecainide | Hepatotoxicity (steatosis) | = | 0 | ALA3137733 | references out of a total of 6 | |||||
15. | ALA652 | Flecainide | Hepatotoxicity (association with vascular disease) | = | 0 | ALA3137732 | references out of a total of 6 | |||||
16. | ALA652 | Flecainide | Hepatotoxicity (granulomatous hepatitis) | = | 0 | ALA3137731 | references out of a total of 6 | |||||
17. | ALA652 | Flecainide | Hepatotoxicity (cirrhosis) | = | 0 | ALA3137730 | references out of a total of 6 | |||||
18. | ALA652 | Flecainide | Hepatotoxicity (chronic liver disease) | = | 0 | ALA3137729 | references out of a total of 6 | |||||
19. | ALA652 | Flecainide | Hepatotoxicity (severe hepatitis) | = | 0 | ALA3137728 | references out of a total of 6 | |||||
20. | ALA652 | Flecainide | Hepatotoxicity (choleostasis) | = | 2 | ALA3137727 | references out of a total of 6 |