| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5188193 | 63 | K(p,uu,brain) | = | 0.02 | ALA5166411 | ||||||
| 2. | ALA5188193 | 63 | Kp | = | 0.06 | ALA5166410 | ||||||
| 3. | ALA5188193 | 63 | Fu | = | 2.2 | % | ALA5166409 | |||||
| 4. | ALA5188193 | 63 | Fu | = | 7.8 | % | ALA5166408 | |||||
| 5. | ALA5188193 | 63 | AUC/dose | = | 23 | ng.hr/ml.mg | ALA5166407 | ng.hr/ml.mg | ||||
| 6. | ALA5188193 | 63 | AUC/dose | = | 108 | ng.hr/ml.mg | ALA5166406 | ng.hr/ml.mg | ||||
| 7. | ALA5188193 | 63 | F | = | 30 | % | ALA5166405 | % | ||||
| 8. | ALA5188193 | 63 | AUC/dose | = | 400 | ng.hr/ml.mg | ALA5166404 | ng.hr/ml.mg | ||||
| 9. | ALA5188193 | 63 | t1/2 | = | 1.5 | hr | ALA5166403 | hr | ||||
| 10. | ALA5188193 | 63 | AUC/dose | = | 1390 | ng.hr/ml.mg | ALA5166402 | ng.hr/ml.mg | ||||
| 11. | ALA5188193 | 63 | Vdss | = | 0.9 | L/Kg | ALA5166401 | L.kg-1 | ||||
| 12. | ALA5188193 | 63 | CL | = | 11 | uL/min/kg | ALA5166400 | mL.min-1.kg-1 | ||||
| 13. | ALA5188193 | 63 | CLH | = | 9 | uL/min | ALA5166399 | uL/min | ||||
| 14. | ALA5188193 | 63 | CLH | = | 6 | uL/min | ALA5166398 | uL/min | ||||
| 15. | ALA5188193 | 63 | CLH | 0 | ALA5166397 | ND | ||||||
| 16. | ALA5188193 | 63 | CLH | 0 | ALA5166396 | ND | ||||||
| 17. | ALA5188193 | 63 | logD | = | 2.2 | ALA5166395 | ||||||
| 18. | ALA5188193 | 63 | EC50 | = | 0.1 | uM | ALA5166394 | 7.00 | nM | Mus musculus | ||
| 19. | ALA5188193 | 63 | EC50 | = | 0.095 | uM | ALA5166393 | 7.02 | nM | Homo sapiens | ||
| 20. | ALA5188193 | 63 | IC50 | = | 0.009 | uM | ALA5166382 | 8.05 | nM | Homo sapiens |
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