# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5188612 | 32 | Activity | 0 | ALA5124043 | Non-Toxic | ||||||
2. | ALA5188612 | 32 | Activity | 0 | ALA5124042 | Non-Toxic | ||||||
3. | ALA5188612 | 32 | Vd | = | 5.14 | L/Kg | ALA5124041 | L.kg-1 | ||||
4. | ALA5188612 | 32 | CL | = | 34.7 | ml/min.kg | ALA5124040 | mL.min-1.kg-1 | ||||
5. | ALA5188612 | 32 | AUC | = | 3380 | ng.hr/ml | ALA5124039 | ng.hr.mL-1 | ||||
6. | ALA5188612 | 32 | AUC | = | 2844 | ng.hr/ml | ALA5124038 | ng.hr.mL-1 | ||||
7. | ALA5188612 | 32 | t1/2 | = | 1.7 | hr | ALA5124037 | hr | ||||
8. | ALA5188612 | 32 | Cmax | = | 3.2 | uM | ALA5124036 | nM | ||||
9. | ALA5188612 | 32 | Cmax | = | 1213 | ng/ml | ALA5124036 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA5188612 | 32 | Tmax | = | 0.5 | hr | ALA5124035 | hr | ||||
11. | ALA5188612 | 32 | Vd | = | 13 | L/Kg | ALA5124034 | L.kg-1 | ||||
12. | ALA5188612 | 32 | CL | = | 56.6 | ml/min.kg | ALA5124033 | mL.min-1.kg-1 | ||||
13. | ALA5188612 | 32 | AUC | = | 2080 | ng.hr/ml | ALA5124032 | ng.hr.mL-1 | ||||
14. | ALA5188612 | 32 | AUC | = | 1664 | ng.hr/ml | ALA5124031 | ng.hr.mL-1 | ||||
15. | ALA5188612 | 32 | t1/2 | = | 2.7 | hr | ALA5124030 | hr | ||||
16. | ALA5188612 | 32 | Cmax | = | 2.9 | uM | ALA5124029 | nM | ||||
17. | ALA5188612 | 32 | Cmax | = | 1096 | ng/ml | ALA5124029 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
18. | ALA5188612 | 32 | Tmax | = | 0.5 | hr | ALA5124028 | hr | ||||
19. | ALA5188612 | 32 | Activity | = | 30.8 | % | ALA5124027 | % | Leishmania infantum | |||
20. | ALA5188612 | 32 | Activity | = | -1.8 | % | ALA5124026 | % | Leishmania infantum |