| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5189703 | 36 | PPB | = | 96.6 | % | ALA5168420 | % | ||||
| 2. | ALA5189703 | 36 | IC50 | > | 30 | uM | ALA5168419 | nM | Homo sapiens | |||
| 3. | ALA5189703 | 36 | Kinetic_solubility | < | 1 | uM | ALA5168418 | nM | ||||
| 4. | ALA5189703 | 36 | Kinetic_solubility | = | 182.1 | uM | ALA5168417 | nM | ||||
| 5. | ALA5189703 | 36 | IC50 | > | 100 | uM | ALA5168416 | nM | Homo sapiens | |||
| 6. | ALA5189703 | 36 | IC50 | > | 100 | uM | ALA5168415 | nM | Mus musculus | |||
| 7. | ALA5189703 | 36 | IC50 | > | 100 | uM | ALA5168414 | nM | Mus musculus | |||
| 8. | ALA5189703 | 36 | F | = | 52.3 | % | ALA5168413 | % | ||||
| 9. | ALA5189703 | 36 | t1/2 | = | 3.5 | hr | ALA5168412 | hr | ||||
| 10. | ALA5189703 | 36 | CL | = | 2993.6 | ml/hr.kg | ALA5168411 | mL.min-1.kg-1 | ||||
| 11. | ALA5189703 | 36 | AUC | = | 1692.7 | ng.hr/ml | ALA5168410 | ng.hr.mL-1 | ||||
| 12. | ALA5189703 | 36 | AUC | = | 1679.3 | ng.hr/ml | ALA5168409 | ng.hr.mL-1 | ||||
| 13. | ALA5189703 | 36 | Cmax | = | 663.7 | ng/ml | ALA5168408 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA5189703 | 36 | t1/2 | = | 3.4 | hr | ALA5168407 | hr | ||||
| 15. | ALA5189703 | 36 | CL | = | 1475.6 | ml/hr.kg | ALA5168406 | mL.min-1.kg-1 | ||||
| 16. | ALA5189703 | 36 | AUC | = | 682.6 | ng.hr/ml | ALA5168405 | ng.hr.mL-1 | ||||
| 17. | ALA5189703 | 36 | AUC | = | 642 | ng.hr/ml | ALA5168404 | ng.hr.mL-1 | ||||
| 18. | ALA5189703 | 36 | Cmax | = | 2797.5 | ng/ml | ALA5168403 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 19. | ALA5189703 | 36 | INH | 0 | ALA5168402 | NA | % | Homo sapiens | ||||
| 20. | ALA5189703 | 36 | INH | = | 23 | % | ALA5168401 | % | Homo sapiens |
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