# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5190430 | 52 | K(p,uu,brain) | = | 0.43 | ALA5166411 | ||||||
2. | ALA5190430 | 52 | Kp | = | 0.23 | ALA5166410 | ||||||
3. | ALA5190430 | 52 | Fu | = | 9 | % | ALA5166409 | |||||
4. | ALA5190430 | 52 | Fu | = | 5 | % | ALA5166408 | |||||
5. | ALA5190430 | 52 | AUC/dose | = | 38 | ng.hr/ml.mg | ALA5166407 | ng.hr/ml.mg | ||||
6. | ALA5190430 | 52 | AUC/dose | = | 67 | ng.hr/ml.mg | ALA5166406 | ng.hr/ml.mg | ||||
7. | ALA5190430 | 52 | F | = | 42 | % | ALA5166405 | % | ||||
8. | ALA5190430 | 52 | AUC/dose | = | 180 | ng.hr/ml.mg | ALA5166404 | ng.hr/ml.mg | ||||
9. | ALA5190430 | 52 | t1/2 | = | 1.3 | hr | ALA5166403 | hr | ||||
10. | ALA5190430 | 52 | AUC/dose | = | 440 | ng.hr/ml.mg | ALA5166402 | ng.hr/ml.mg | ||||
11. | ALA5190430 | 52 | Vdss | = | 1.3 | L/Kg | ALA5166401 | L.kg-1 | ||||
12. | ALA5190430 | 52 | CL | = | 37 | uL/min/kg | ALA5166400 | mL.min-1.kg-1 | ||||
13. | ALA5190430 | 52 | CLH | = | 57 | uL/min | ALA5166399 | uL/min | ||||
14. | ALA5190430 | 52 | CLH | = | 49 | uL/min | ALA5166398 | uL/min | ||||
15. | ALA5190430 | 52 | CLH | < | 14 | microL/min/mg | ALA5166397 | mL.min-1.g-1 | ||||
16. | ALA5190430 | 52 | CLH | < | 14 | microL/min/mg | ALA5166396 | mL.min-1.g-1 | ||||
17. | ALA5190430 | 52 | logD | = | 1.4 | ALA5166395 | ||||||
18. | ALA5190430 | 52 | EC50 | = | 0.56 | uM | ALA5166394 | 6.25 | nM | Mus musculus | ||
19. | ALA5190430 | 52 | EC50 | = | 0.88 | uM | ALA5166393 | 6.06 | nM | Homo sapiens | ||
20. | ALA5190430 | 52 | Ratio | = | 0.6 | ALA5166384 |