# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5190717 | 37 | Kinetic_solubility | = | 66 | uM | ALA5165217 | nM | ||||
2. | ALA5190717 | 37 | F | = | 15 | % | ALA5165216 | % | ||||
3. | ALA5190717 | 37 | t1/2 | = | 1.2 | hr | ALA5165215 | hr | ||||
4. | ALA5190717 | 37 | AUC | = | 1000 | hr.ng/ml | ALA5165214 | ng.hr.mL-1 | ||||
5. | ALA5190717 | 37 | Cmax | = | 1083 | ng/ml | ALA5165213 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
6. | ALA5190717 | 37 | Vdss | = | 1.1 | L/Kg | ALA5165212 | L.kg-1 | ||||
7. | ALA5190717 | 37 | AUC | = | 2075 | hr.ng/ml | ALA5165211 | ng.hr.mL-1 | ||||
8. | ALA5190717 | 37 | Selectivity ratio | = | 150 | ALA5165210 | ||||||
9. | ALA5190717 | 37 | GI50 | = | 43 | nM | ALA5165208 | nM | Homo sapiens | |||
10. | ALA5190717 | 37 | Ki | < | 0.02 | nM | ALA5165207 | nM | Homo sapiens | |||
11. | ALA5190717 | 37 | CL | = | 25 | ml/min.kg | ALA5165203 | mL.min-1.kg-1 | ||||
12. | ALA5190717 | 37 | GI50 | = | 2500 | nM | ALA5165200 | nM | Homo sapiens | |||
13. | ALA5190717 | 37 | GI50 | = | 17 | nM | ALA5165199 | nM | Homo sapiens |