| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5191411 | (-)-25 | F | = | 0.3 | % | ALA5162119 | % | ||||
| 2. | ALA5191411 | (-)-25 | CL | = | 108 | ml/min.kg | ALA5162117 | mL.min-1.kg-1 | ||||
| 3. | ALA5191411 | (-)-25 | Vd | = | 18400 | ml/kg | ALA5162114 | L.kg-1 | ||||
| 4. | ALA5191411 | (-)-25 | Kel | = | 0.102 | /min | ALA5162112 | /min | ||||
| 5. | ALA5191411 | (-)-25 | Kel | = | 0.006 | /min | ALA5162111 | /min | ||||
| 6. | ALA5191411 | (-)-25 | t1/2 | = | 6.78 | min | ALA5162109 | hr | ||||
| 7. | ALA5191411 | (-)-25 | t1/2 | = | 118 | min | ALA5162108 | hr | ||||
| 8. | ALA5191411 | (-)-25 | AUC | = | 512 | ng.min/ml | ALA5162106 | ng.hr.mL-1 | ||||
| 9. | ALA5191411 | (-)-25 | AUC | = | 185000 | ng.min/ml | ALA5162105 | ng.hr.mL-1 | ||||
| 10. | ALA5191411 | (-)-25 | AUCt | = | 484 | ng.min/ml | ALA5162103 | ng.hr.mL-1 | ||||
| 11. | ALA5191411 | (-)-25 | AUCt | = | 181000 | ng.min/ml | ALA5162102 | ng.hr.mL-1 | ||||
| 12. | ALA5191411 | (-)-25 | Cmax | = | 36.4 | ng/ml | ALA5162100 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA5191411 | (-)-25 | Cmax | = | 8320 | ng/ml | ALA5162099 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA5191411 | (-)-25 | Tmax | = | 5 | min | ALA5162097 | hr | ||||
| 15. | ALA5191411 | (-)-25 | Tmax | = | 5 | min | ALA5162096 | hr | ||||
| 16. | ALA5191411 | (-)-25 | deltaG | = | -1 | kJ/mol | ALA5161940 | kJ/mol | Homo sapiens | |||
| 17. | ALA5191411 | (-)-25 | IC50 | = | 19 | nM | ALA5161939 | 7.72 | nM | Homo sapiens | ||
| 18. | ALA5191411 | (-)-25 | IC50 | = | 7410 | nM | ALA5161939 | 5.13 | nM | Homo sapiens |
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