Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5192865	14; KT-531	AUC/dose	=	79	hr.ng/ml	ALA5158397			hr.ng/ml
2.	ALA5192865	14; KT-531	AUC	=	1519	hr.ng/ml	ALA5158396			ng.hr.mL-1
3.	ALA5192865	14; KT-531	AUClast	=	1576	hr.ng/ml	ALA5158395			ng.hr.mL-1
4.	ALA5192865	14; KT-531	Cmax	=	493	ng/ml	ALA5158394		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
5.	ALA5192865	14; KT-531	t1/2	=	1.05	hr	ALA5158393			hr
6.	ALA5192865	14; KT-531	t1/2	=	41	min	ALA5158392			hr
7.	ALA5192865	14; KT-531	Time	=	52	min	ALA5158362			hr	Homo sapiens
8.	ALA5192865	14; KT-531	IC50	=	3.3	uM	ALA5158361	5.48		nM	Homo sapiens
9.	ALA5192865	14; KT-531	IC50	=	3.9	uM	ALA5158359	5.41		nM	Homo sapiens
10.	ALA5192865	14; KT-531	IC50	=	3	uM	ALA5158358	5.52		nM	Homo sapiens
11.	ALA5192865	14; KT-531	IC50	=	1.43	uM	ALA5158357	5.84		nM
12.	ALA5192865	14; KT-531	IC50	=	0.173	uM	ALA5158356	6.76		nM
13.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158355			nM	Homo sapiens
14.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158354			nM	Homo sapiens
15.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158353			nM	Homo sapiens
16.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158352			nM	Homo sapiens
17.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158351			nM	Homo sapiens
18.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158350			nM	Homo sapiens
19.	ALA5192865	14; KT-531	IC50	>	1	uM	ALA5158349			nM	Homo sapiens
20.	ALA5192865	14; KT-531	Ki	=	17.3	nM	ALA5158348	7.76		nM	Homo sapiens