# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5194648 | 76 | F | = | 41.5 | % | ALA5142429 | % | ||||
2. | ALA5194648 | 76 | AUC | = | 3160 | ng/mL.hr | ALA5142428 | ng.hr.mL-1 | ||||
3. | ALA5194648 | 76 | Tmax | = | 1 | hr | ALA5142427 | hr | ||||
4. | ALA5194648 | 76 | Cmax | = | 1080 | ng/ml | ALA5142426 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5194648 | 76 | AUC | = | 757 | ng/mL.hr | ALA5142425 | ng.hr.mL-1 | ||||
6. | ALA5194648 | 76 | C0 | = | 1170 | ng/ml | ALA5142424 | ng/ml | ||||
7. | ALA5194648 | 76 | Vdss | = | 1.81 | L/Kg | ALA5142423 | L.kg-1 | ||||
8. | ALA5194648 | 76 | CL | = | 22 | ml/min.kg | ALA5142422 | mL.min-1.kg-1 | ||||
9. | ALA5194648 | 76 | beta t1/2 | = | 1.22 | hr | ALA5142421 | hr | ||||
10. | ALA5194648 | 76 | Fu | = | 1.1 | % | ALA5142420 | |||||
11. | ALA5194648 | 76 | t1/2 | = | 57.2 | min | ALA5142419 | hr | ||||
12. | ALA5194648 | 76 | t1/2 | = | 47.3 | min | ALA5142418 | hr | ||||
13. | ALA5194648 | 76 | Kinetic_solubility | = | 61 | uM | ALA5142417 | nM | ||||
14. | ALA5194648 | 76 | logD | = | 3.09 | ALA5142416 | ||||||
15. | ALA5194648 | 76 | INH | 0 | ALA5142415 | NA | % | Homo sapiens | ||||
16. | ALA5194648 | 76 | INH | 0 | ALA5142414 | NA | % | Homo sapiens | ||||
17. | ALA5194648 | 76 | pIC50 | = | 7.46 | ALA5142410 | 7.46 | nM | Homo sapiens |