# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5195160 | 8e | BPR | = | 0.2 | ALA5167423 | ||||||
2. | ALA5195160 | 8e | AUC | = | 426 | ng/mL.hr | ALA5167422 | ng.hr.mL-1 | ||||
3. | ALA5195160 | 8e | Cmax | = | 1282 | ng/ml | ALA5167421 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA5195160 | 8e | Tmax | = | 0.17 | hr | ALA5167420 | hr | ||||
5. | ALA5195160 | 8e | t1/2 | = | 0.12 | hr | ALA5167419 | hr | ||||
6. | ALA5195160 | 8e | Kp | = | 0.19 | ALA5167418 | ||||||
7. | ALA5195160 | 8e | Ct | = | 55.9 | ng/g | ALA5167417 | ng/g | ||||
8. | ALA5195160 | 8e | Cp | = | 297 | ng/ml | ALA5167416 | ng/ml | ||||
9. | ALA5195160 | 8e | PPB | = | 1.1 | % | ALA5167415 | % | ||||
10. | ALA5195160 | 8e | PPB | = | 0.2 | % | ALA5167414 | % | ||||
11. | ALA5195160 | 8e | CLH | = | 979.5 | ml/min.kg | ALA5167413 | mL.min-1.kg-1 | ||||
12. | ALA5195160 | 8e | CLH | = | 59.4 | ml/min.kg | ALA5167412 | mL.min-1.kg-1 | ||||
13. | ALA5195160 | 8e | EC50 | = | 0.013 | uM | ALA5167411 | 7.89 | nM | Homo sapiens | ||
14. | ALA5195160 | 8e | Emax | = | 126.8 | % | ALA5167410 | % | Homo sapiens | |||
15. | ALA5195160 | 8e | Ki | = | 71 | nM | ALA5167409 | 7.15 | nM | Homo sapiens | ||
16. | ALA5195160 | 8e | CL | = | 14.1 | ml/min.kg | ALA5167408 | mL.min-1.kg-1 | ||||
17. | ALA5195160 | 8e | t1/2 | = | 0.41 | hr | ALA5167407 | hr | ||||
18. | ALA5195160 | 8e | AUC | = | 304 | ng/mL.hr | ALA5167406 | ng.hr.mL-1 | ||||
19. | ALA5195160 | 8e | Vdss | = | 0.34 | L/Kg | ALA5167405 | L.kg-1 |