# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5195355 | 28 | Ratio IC50/EC50 | = | 5000 | ALA5116034 | ||||||
2. | ALA5195355 | 28 | F | = | 55 | % | ALA5116033 | % | ||||
3. | ALA5195355 | 28 | AUC | = | 4661 | ng.hr/ml | ALA5116032 | ng.hr.mL-1 | ||||
4. | ALA5195355 | 28 | Cmax | = | 324 | ng/ml | ALA5116031 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5195355 | 28 | Vdss | = | 12.9 | L/Kg | ALA5116030 | L.kg-1 | ||||
6. | ALA5195355 | 28 | Vdss | = | 17 | L/Kg | ALA5116029 | L.kg-1 | ||||
7. | ALA5195355 | 28 | CL | = | 11.4 | ml/min.kg | ALA5116028 | mL.min-1.kg-1 | ||||
8. | ALA5195355 | 28 | CL | = | 58 | ml/min.kg | ALA5116027 | mL.min-1.kg-1 | ||||
9. | ALA5195355 | 28 | t1/2 | = | 16.9 | min | ALA5116026 | hr | ||||
10. | ALA5195355 | 28 | t1/2 | = | 5.3 | min | ALA5116025 | hr | ||||
11. | ALA5195355 | 28 | CLH | = | 94.3 | ml/min/g | ALA5116024 | mL.min-1.g-1 | ||||
12. | ALA5195355 | 28 | t1/2 | = | 15 | min | ALA5116023 | hr | ||||
13. | ALA5195355 | 28 | CLH | = | 4 | ml/min/g | ALA5116022 | mL.min-1.g-1 | ||||
14. | ALA5195355 | 28 | t1/2 | = | 347 | min | ALA5116021 | hr | ||||
15. | ALA5195355 | 28 | t1/2 | > | 693 | min | ALA5116020 | hr | ||||
16. | ALA5195355 | 28 | t1/2 | > | 693 | min | ALA5116019 | hr | ||||
17. | ALA5195355 | 28 | IC50 | > | 10 | uM | ALA5116018 | nM | Homo sapiens | |||
18. | ALA5195355 | 28 | IC50 | > | 10 | uM | ALA5116017 | nM | Homo sapiens | |||
19. | ALA5195355 | 28 | IC50 | = | 7.5 | uM | ALA5116016 | 5.12 | nM | Homo sapiens | ||
20. | ALA5195355 | 28 | IC50 | = | 10 | uM | ALA5116015 | 5.00 | nM | Homo sapiens |