# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5195378 | 12 | Ki | = | 4.1 | 10^4/M | ALA5159127 | 10^4/M | Homo sapiens | |||
2. | ALA5195378 | 12 | Drug uptake | 0 | ALA5159126 | Active | ||||||
3. | ALA5195378 | 12 | Drug uptake | = | 4.3 | % | ALA5159125 | % | ||||
4. | ALA5195378 | 12 | Drug uptake | = | 20.7 | % | ALA5159124 | % | ||||
5. | ALA5195378 | 12 | Drug uptake | = | 23.1 | % | ALA5159123 | % | ||||
6. | ALA5195378 | 12 | Activity | 0 | ALA5159122 | Active | Homo sapiens | |||||
7. | ALA5195378 | 12 | Activity | 0 | ALA5159121 | Active | Homo sapiens | |||||
8. | ALA5195378 | 12 | deltaTm | = | 10 | degrees C | ALA5159120 | degrees C | Homo sapiens | |||
9. | ALA5195378 | 12 | Selectivity Index | = | 49 | ALA5159119 | ||||||
10. | ALA5195378 | 12 | Selectivity Index | = | 5.7 | ALA5159118 | ||||||
11. | ALA5195378 | 12 | Selectivity Index | = | 9.8 | ALA5159117 | ||||||
12. | ALA5195378 | 12 | IC50 | = | 2.94 | uM | ALA5159116 | 5.53 | nM | Homo sapiens | ||
13. | ALA5195378 | 12 | IC50 | = | 0.3 | uM | ALA5159115 | 6.52 | nM | Homo sapiens | ||
14. | ALA5195378 | 12 | IC50 | = | 0.51 | uM | ALA5159114 | 6.29 | nM | Leishmania major | ||
15. | ALA5195378 | 12 | IC50 | = | 0.06 | uM | ALA5159113 | 7.22 | nM | Trypanosoma brucei | ||
16. | ALA5195378 | 12 | Drug uptake | 0 | ALA5159112 | Active | ||||||
17. | ALA5195378 | 12 | Drug uptake | 0 | ALA5159111 | Active |