# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5195846 | 2a | INH | 0 | ALA5116792 | NA | % | Homo sapiens | ||||
2. | ALA5195846 | 2a | INH | 0 | ALA5116791 | NA | % | Homo sapiens | ||||
3. | ALA5195846 | 2a | INH | 0 | ALA5116790 | NA | % | Homo sapiens | ||||
4. | ALA5195846 | 2a | INH | 0 | ALA5116789 | NA | % | Homo sapiens | ||||
5. | ALA5195846 | 2a | AUC | = | 2 | uM.hr | ALA5116788 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
6. | ALA5195846 | 2a | Cmax | = | 1.23 | uM | ALA5116787 | nM | ||||
7. | ALA5195846 | 2a | t1/2 | > | 4 | hr | ALA5116786 | hr | ||||
8. | ALA5195846 | 2a | t1/2 | > | 4 | hr | ALA5116785 | hr | ||||
9. | ALA5195846 | 2a | CLH | = | 0.1 | uL/min | ALA5116784 | uL/min | ||||
10. | ALA5195846 | 2a | CLH | = | 0.2 | uL/min | ALA5116783 | uL/min | ||||
11. | ALA5195846 | 2a | Activity | 0 | ALA5116782 | Active | ||||||
12. | ALA5195846 | 2a | Activity | 0 | ALA5116781 | Active | ||||||
13. | ALA5195846 | 2a | Activity | 0 | ALA5116780 | Active | ||||||
14. | ALA5195846 | 2a | IC50 | = | 25.6 | nM | ALA5116778 | 7.59 | nM | Homo sapiens | ||
15. | ALA5195846 | 2a | INH | 0 | ALA5116777 | NA | % | Homo sapiens | ||||
16. | ALA5195846 | 2a | INH | 0 | ALA5116776 | NA | % | Homo sapiens | ||||
17. | ALA5195846 | 2a | Ratio IC50 | = | 136.8 | ALA5116775 | ||||||
18. | ALA5195846 | 2a | IC50 | = | 328.3 | nM | ALA5116774 | 6.48 | nM | Homo sapiens | ||
19. | ALA5195846 | 2a | IC50 | = | 2.4 | nM | ALA5116773 | 8.62 | nM | Homo sapiens |