# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112570 | ||||||
2. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112569 | ||||||
3. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112568 | ||||||
4. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112567 | ||||||
5. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112566 | ||||||
6. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112565 | ||||||
7. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112564 | ||||||
8. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112563 | ||||||
9. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112562 | ||||||
10. | ALA5196686 | 35 | Ratio IC50 | = | 250 | ALA5112561 | ||||||
11. | ALA5196686 | 35 | INH | 0 | ALA5112560 | Active | % | Homo sapiens | ||||
12. | ALA5196686 | 35 | INH | 0 | ALA5112559 | Active | % | Homo sapiens | ||||
13. | ALA5196686 | 35 | F | = | 7.5 | % | ALA5112548 | % | ||||
14. | ALA5196686 | 35 | Vdss | = | 2.37 | L/Kg | ALA5112547 | L.kg-1 | ||||
15. | ALA5196686 | 35 | AUC | = | 229 | hr.ug/L | ALA5112546 | ng.hr.mL-1 | ||||
16. | ALA5196686 | 35 | AUC | = | 306 | hr.ug/L | ALA5112545 | ng.hr.mL-1 | ||||
17. | ALA5196686 | 35 | Cmax | = | 313 | ug/L | ALA5112544 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
18. | ALA5196686 | 35 | CL | = | 244 | L/hr/kg | ALA5112543 | mL.min-1.kg-1 | ||||
19. | ALA5196686 | 35 | Tmax | = | 0.33 | hr | ALA5112542 | hr | ||||
20. | ALA5196686 | 35 | t1/2 | = | 1.44 | hr | ALA5112541 | hr |