# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5196906 | 12; PXS-5131 | Activity | 0 | ALA5106552 | Active | Mus musculus | |||||
2. | ALA5196906 | 12; PXS-5131 | Activity | > | 50 | % | ALA5106551 | % | Mus musculus | |||
3. | ALA5196906 | 12; PXS-5131 | Activity | 0 | ALA5106550 | Active | Mus musculus | |||||
4. | ALA5196906 | 12; PXS-5131 | Activity | > | 60 | % | ALA5106549 | % | ||||
5. | ALA5196906 | 12; PXS-5131 | INH | 0 | ALA5106548 | Active | % | |||||
6. | ALA5196906 | 12; PXS-5131 | INH | 0 | ALA5106547 | NA | % | |||||
7. | ALA5196906 | 12; PXS-5131 | INH | 0 | ALA5106546 | Active | % | |||||
8. | ALA5196906 | 12; PXS-5131 | INH | 0 | ALA5106545 | Active | % | |||||
9. | ALA5196906 | 12; PXS-5131 | AUC | = | 265 | hr.ng/ml | ALA5106544 | ng.hr.mL-1 | ||||
10. | ALA5196906 | 12; PXS-5131 | Cmax | = | 199 | ng/ml | ALA5106543 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
11. | ALA5196906 | 12; PXS-5131 | Tmax | = | 20 | min | ALA5106542 | hr | ||||
12. | ALA5196906 | 12; PXS-5131 | Kinact | = | 0.14 | /min | ALA5106541 | /min | Homo sapiens | |||
13. | ALA5196906 | 12; PXS-5131 | Kinact | = | 0.1 | /min | ALA5106540 | /min | Homo sapiens | |||
14. | ALA5196906 | 12; PXS-5131 | Ki | = | 0.71 | uM | ALA5106539 | 6.15 | nM | Homo sapiens | ||
15. | ALA5196906 | 12; PXS-5131 | Ki | = | 0.008 | uM | ALA5106538 | 8.10 | nM | Homo sapiens | ||
16. | ALA5196906 | 12; PXS-5131 | IC50 | > | 10 | uM | ALA5106535 | nM | Homo sapiens | |||
17. | ALA5196906 | 12; PXS-5131 | IC50 | > | 10 | uM | ALA5106534 | nM | Homo sapiens | |||
18. | ALA5196906 | 12; PXS-5131 | IC50 | > | 10 | uM | ALA5106533 | nM | Homo sapiens | |||
19. | ALA5196906 | 12; PXS-5131 | IC50 | > | 10 | uM | ALA5106532 | nM | Homo sapiens | |||
20. | ALA5196906 | 12; PXS-5131 | IC50 | > | 10 | uM | ALA5106531 | nM | Homo sapiens |