Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5197758	22	F	=	66.6	%	ALA5154534			%
2.	ALA5197758	22	AUC	=	54136	nM.hr	ALA5154533		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1
3.	ALA5197758	22	Cmax	=	25650	nM	ALA5154532			nM
4.	ALA5197758	22	CL	=	9.58	ml/min.kg	ALA5154531			mL.min-1.kg-1
5.	ALA5197758	22	Vdss	=	0.501	L/Kg	ALA5154530			L.kg-1
6.	ALA5197758	22	beta t1/2	=	1.5	hr	ALA5154529			hr
7.	ALA5197758	22	IC50	>	100	uM	ALA5154528			nM	Homo sapiens
8.	ALA5197758	22	IC50	>	100	uM	ALA5154527			nM	Homo sapiens
9.	ALA5197758	22	IC50	=	75	uM	ALA5154526	4.12		nM	Homo sapiens
10.	ALA5197758	22	IC50	>	100	uM	ALA5154525			nM	Homo sapiens
11.	ALA5197758	22	IC50	>	100	uM	ALA5154524			nM	Homo sapiens
12.	ALA5197758	22	IC50	>	100	uM	ALA5154523			nM	Homo sapiens
13.	ALA5197758	22	IC50	=	8.21	uM	ALA5154522	5.09		nM	Homo sapiens
14.	ALA5197758	22	CLH	<	6.4	microL/min/mg	ALA5154521			mL.min-1.g-1
15.	ALA5197758	22	CLH	<	10.8	microL/min/mg	ALA5154520			mL.min-1.g-1
16.	ALA5197758	22	CLH	=	34.2	microL/min/mg	ALA5154519			mL.min-1.g-1
17.	ALA5197758	22	CLH	<	9.6	microL/min/mg	ALA5154518			mL.min-1.g-1
18.	ALA5197758	22	CLH	=	16.9	microL/min/mg	ALA5154517			mL.min-1.g-1
19.	ALA5197758	22	CLH	=	24.2	microL/min/mg	ALA5154516			mL.min-1.g-1
20.	ALA5197758	22	Fu	=	15.6	%	ALA5154515