# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158069 | NA | Homo sapiens | |||||
2. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158068 | NA | Homo sapiens | |||||
3. | ALA5198644 | (R)-2; ErSO-DFP | Stability | = | 13 | % | ALA5158067 | % | ||||
4. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158066 | Active | Homo sapiens | |||||
5. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158065 | Non-Toxic | ||||||
6. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158064 | Active | Homo sapiens | |||||
7. | ALA5198644 | (R)-2; ErSO-DFP | MTD | > | 50 | mg kg-1 | ALA5158063 | mg kg-1 | ||||
8. | ALA5198644 | (R)-2; ErSO-DFP | MTD | = | 95 | mg kg-1 | ALA5158062 | mg kg-1 | ||||
9. | ALA5198644 | (R)-2; ErSO-DFP | MTD | > | 200 | mg kg-1 | ALA5158061 | mg kg-1 | ||||
10. | ALA5198644 | (R)-2; ErSO-DFP | Vdss | = | 2.8 | L/Kg | ALA5158060 | L.kg-1 | ||||
11. | ALA5198644 | (R)-2; ErSO-DFP | CL | = | 52 | ml/min.kg | ALA5158059 | mL.min-1.kg-1 | ||||
12. | ALA5198644 | (R)-2; ErSO-DFP | MRT | = | 0.9 | hr | ALA5158058 | hr | ||||
13. | ALA5198644 | (R)-2; ErSO-DFP | t1/2 | = | 18 | min | ALA5158057 | hr | ||||
14. | ALA5198644 | (R)-2; ErSO-DFP | AUC | = | 6.3 | hr.microg/ml | ALA5158056 | ng.hr.mL-1 | ||||
15. | ALA5198644 | (R)-2; ErSO-DFP | t1/2 | = | 56 | min | ALA5158053 | hr | ||||
16. | ALA5198644 | (R)-2; ErSO-DFP | F | = | 6 | % | ALA5158052 | % | ||||
17. | ALA5198644 | (R)-2; ErSO-DFP | Cmax | = | 14.7 | ug ml-1 | ALA5158051 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
18. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158050 | NA | Homo sapiens | |||||
19. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158049 | Dde | Homo sapiens | |||||
20. | ALA5198644 | (R)-2; ErSO-DFP | Activity | 0 | ALA5158049 | Tde | Homo sapiens |