# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5199428 | 14c | TGI | = | 85 | % | ALA5164015 | % | Mus musculus | |||
2. | ALA5199428 | 14c | TGI | = | 68 | % | ALA5164014 | % | Mus musculus | |||
3. | ALA5199428 | 14c | TGI | = | 26 | % | ALA5164013 | % | Mus musculus | |||
4. | ALA5199428 | 14c | TGI | = | 44 | % | ALA5164012 | % | Mus musculus | |||
5. | ALA5199428 | 14c | IC50 | > | 10000 | nM | ALA5164011 | nM | Homo sapiens | |||
6. | ALA5199428 | 14c | IC50 | > | 10000 | nM | ALA5164010 | nM | Homo sapiens | |||
7. | ALA5199428 | 14c | IC50 | = | 443.5 | nM | ALA5164009 | 6.35 | nM | Homo sapiens | ||
8. | ALA5199428 | 14c | IC50 | = | 240.2 | nM | ALA5164008 | 6.62 | nM | Homo sapiens | ||
9. | ALA5199428 | 14c | Ki | > | 10000 | nM | ALA5164007 | nM | Homo sapiens | |||
10. | ALA5199428 | 14c | Ki | > | 10000 | nM | ALA5164006 | nM | Homo sapiens | |||
11. | ALA5199428 | 14c | Ki | = | 503.3 | nM | ALA5164005 | 6.30 | nM | Homo sapiens | ||
12. | ALA5199428 | 14c | F | = | 119 | % | ALA5164004 | % | ||||
13. | ALA5199428 | 14c | MRT | = | 0.95 | hr | ALA5164003 | hr | ||||
14. | ALA5199428 | 14c | CL | = | 33.5 | ml/min.kg | ALA5164002 | mL.min-1.kg-1 | ||||
15. | ALA5199428 | 14c | AUCt | = | 10022 | hr.ng/ml | ALA5164001 | ng.hr.mL-1 | ||||
16. | ALA5199428 | 14c | Cmax | = | 8411 | ng/ml | ALA5164000 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
17. | ALA5199428 | 14c | Tmax | = | 0.25 | hr | ALA5163999 | hr | ||||
18. | ALA5199428 | 14c | t1/2 | = | 0.83 | hr | ALA5163998 | hr | ||||
19. | ALA5199428 | 14c | Kel | = | 0.844 | /hr | ALA5163997 | /hr | ||||
20. | ALA5199428 | 14c | Vdss | = | 0.92 | L/Kg | ALA5163996 | L.kg-1 |