# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5203652 | KLK5(1)-tag | t1/2 | = | 4.4 | hr | ALA5140208 | hr | ||||
2. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140206 | NA | ||||||
3. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140205 | NA | ||||||
4. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140204 | NA | ||||||
5. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140203 | NA | ||||||
6. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140202 | NA | ||||||
7. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140200 | Active | ||||||
8. | ALA5203652 | KLK5(1)-tag | Stability | 0 | ALA5140199 | Unstable | % | |||||
9. | ALA5203652 | KLK5(1)-tag | Stability | 0 | ALA5140198 | Unstable | % | |||||
10. | ALA5203652 | KLK5(1)-tag | Stability | 0 | ALA5140197 | Unstable | % | |||||
11. | ALA5203652 | KLK5(1)-tag | t1/2 | = | 5.8 | hr | ALA5140196 | hr | ||||
12. | ALA5203652 | KLK5(1)-tag | Drug uptake | 0 | ALA5140195 | Active | ||||||
13. | ALA5203652 | KLK5(1)-tag | t1/2 | = | 5.1 | hr | ALA5140194 | hr | ||||
14. | ALA5203652 | KLK5(1)-tag | Cp | = | 20 | uM | ALA5140193 | uM | ||||
15. | ALA5203652 | KLK5(1)-tag | Ki | = | 4.1 | nM | ALA5140192 | 8.39 | nM | Mus musculus | ||
16. | ALA5203652 | KLK5(1)-tag | Ki | = | 1.4 | nM | ALA5140191 | 8.85 | nM | Mus musculus | ||
17. | ALA5203652 | KLK5(1)-tag | Kd | = | 7 | uM | ALA5140190 | 5.16 | nM | Mus musculus | ||
18. | ALA5203652 | KLK5(1)-tag | Kd | = | 119 | nM | ALA5140189 | 6.92 | nM | Homo sapiens | ||
19. | ALA5203652 | KLK5(1)-tag | t1/2 | = | 90 | hr | ALA5140188 | hr | ||||
20. | ALA5203652 | KLK5(1)-tag | Ki | = | 1.2 | nM | ALA5140186 | 8.92 | nM | Homo sapiens |