# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5203721 | 2 | Activity | 0 | ALA5161543 | NA | Mus musculus | |||||
2. | ALA5203721 | 2 | INH | 0 | ALA5161542 | Active | % | Rattus norvegicus | ||||
3. | ALA5203721 | 2 | INH | 0 | ALA5161541 | Active | % | Rattus norvegicus | ||||
4. | ALA5203721 | 2 | INH | = | 39.48 | % | ALA5161540 | % | Rattus norvegicus | |||
5. | ALA5203721 | 2 | Vd | = | 0.183 | L/Kg | ALA5161538 | L.kg-1 | ||||
6. | ALA5203721 | 2 | CL | = | 0.038 | L/Kg.hr | ALA5161537 | L/Kg.hr | ||||
7. | ALA5203721 | 2 | t1/2 | = | 4.8 | hr | ALA5161536 | hr | ||||
8. | ALA5203721 | 2 | Cmax | = | 1247.1 | ug/L | ALA5161535 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA5203721 | 2 | Tmax | = | 1 | hr | ALA5161534 | hr | ||||
10. | ALA5203721 | 2 | IC50 | = | 12.39 | uM | ALA5161533 | 4.91 | nM | Homo sapiens | ||
11. | ALA5203721 | 2 | IC50 | = | 778.7 | nM | ALA5161532 | 6.11 | nM | Homo sapiens | ||
12. | ALA5203721 | 2 | IC50 | = | 94.7 | nM | ALA5161531 | 7.02 | nM | Homo sapiens | ||
13. | ALA5203721 | 2 | 2TT | > | 128 | ug ml-1 | ALA5161530 | ug ml-1 | Homo sapiens | |||
14. | ALA5203721 | 2 | EC | > | 128 | ug ml-1 | ALA5161529 | ug ml-1 | Homo sapiens | |||
15. | ALA5203721 | 2 | EC | = | 33.05 | uM | ALA5161528 | uM | Homo sapiens | |||
16. | ALA5203721 | 2 | AUC | = | 6351.2 | hr.ug/L | ALA5161527 | ng.hr.mL-1 | ||||
17. | ALA5203721 | 2 | AUC | = | 6754.4 | hr.ug/L | ALA5161526 | ng.hr.mL-1 | ||||
18. | ALA5203721 | 2 | INH | 0 | ALA5161525 | Active | % | Rattus norvegicus |