# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5204764 | 11a | BPR | = | 2.9 | ALA5145681 | ||||||
2. | ALA5204764 | 11a | Drug uptake | = | 134 | ng/g | ALA5145680 | ng/g | ||||
3. | ALA5204764 | 11a | Cp | = | 45.8 | ng/ml | ALA5145679 | ng/ml | ||||
4. | ALA5204764 | 11a | AUC | = | 747 | hr.ng/ml | ALA5145678 | ng.hr.mL-1 | ||||
5. | ALA5204764 | 11a | Vdss | = | 5.5 | L/Kg | ALA5145677 | L.kg-1 | ||||
6. | ALA5204764 | 11a | C0 | = | 5.5 | ng/ml | ALA5145676 | ng/ml | ||||
7. | ALA5204764 | 11a | t1/2 | = | 4.4 | hr | ALA5145675 | hr | ||||
8. | ALA5204764 | 11a | CL | = | 22 | ml/min.kg | ALA5145674 | mL.min-1.kg-1 | ||||
9. | ALA5204764 | 11a | Fu | = | 1.5 | % | ALA5145672 | |||||
10. | ALA5204764 | 11a | Fu | = | 0.3 | % | ALA5145671 | |||||
11. | ALA5204764 | 11a | CLH | = | 287.1 | ml/min.kg | ALA5145670 | mL.min-1.kg-1 | ||||
12. | ALA5204764 | 11a | CLH | = | 144.7 | ml/min.kg | ALA5145669 | mL.min-1.kg-1 | ||||
13. | ALA5204764 | 11a | INH | < | 50 | % | ALA5145667 | % | Homo sapiens | |||
14. | ALA5204764 | 11a | Ki | = | 2463.8 | nM | ALA5145666 | 5.61 | nM | Homo sapiens | ||
15. | ALA5204764 | 11a | INH | = | 67 | % | ALA5145665 | % | Homo sapiens | |||
16. | ALA5204764 | 11a | INH | < | 50 | % | ALA5145664 | % | Homo sapiens | |||
17. | ALA5204764 | 11a | INH | < | 50 | % | ALA5145663 | % | Homo sapiens | |||
18. | ALA5204764 | 11a | pIC50 | = | 6.52 | ALA5145660 | 6.52 | nM | Homo sapiens | |||
19. | ALA5204764 | 11a | Ki | = | 299.4 | nM | ALA5145660 | 6.52 | nM | Homo sapiens | ||
20. | ALA5204764 | 11a | Fu | = | 1.5 | % | ALA5250297 |