# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5205032 | 1; GS-5734 | Survival | = | 100 | % | ALA5108811 | % | Henipavirus nipahense | |||
2. | ALA5205032 | 1; GS-5734 | t1/2 | = | 5 | min | ALA5108810 | hr | ||||
3. | ALA5205032 | 1; GS-5734 | t1/2 | = | 14 | hr | ALA5108809 | hr | ||||
4. | ALA5205032 | 1; GS-5734 | t1/2 | = | 14 | hr | ALA5108808 | hr | ||||
5. | ALA5205032 | 1; GS-5734 | AUClast | = | 7.5 | uM.hr | ALA5108807 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
6. | ALA5205032 | 1; GS-5734 | AUC | = | 5 | uM.hr | ALA5108806 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
7. | ALA5205032 | 1; GS-5734 | Vdss | = | 1.22 | L/Kg | ALA5108805 | L.kg-1 | ||||
8. | ALA5205032 | 1; GS-5734 | t1/2 | = | 60 | min | ALA5108804 | hr | ||||
9. | ALA5205032 | 1; GS-5734 | CL | = | 0.86 | L/hr/kg | ALA5108803 | mL.min-1.kg-1 | ||||
10. | ALA5205032 | 1; GS-5734 | t1/2 | = | 23 | min | ALA5108802 | hr | ||||
11. | ALA5205032 | 1; GS-5734 | Drug metabolism | = | 1.28 | nmol/g | ALA5108801 | nmol/g | ||||
12. | ALA5205032 | 1; GS-5734 | AUClast | = | 18.2 | uM.hr | ALA5108800 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
13. | ALA5205032 | 1; GS-5734 | AUC | = | 7 | uM.hr | ALA5108799 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
14. | ALA5205032 | 1; GS-5734 | Vdss | = | 0.34 | L/Kg | ALA5108798 | L.kg-1 | ||||
15. | ALA5205032 | 1; GS-5734 | t1/2 | = | 11 | min | ALA5108797 | hr | ||||
16. | ALA5205032 | 1; GS-5734 | CL | = | 2.6 | L/hr/kg | ALA5108796 | mL.min-1.kg-1 | ||||
17. | ALA5205032 | 1; GS-5734 | Ratio | = | 12 | ALA5108781 | Middle East respiratory syndrome-related coronavirus | |||||
18. | ALA5205032 | 1; GS-5734 | EC50 | = | 0.074 | uM | ALA5108780 | 7.13 | nM | Middle East respiratory syndrome-related coronavirus | ||
19. | ALA5205032 | 1; GS-5734 | EC50 | = | 0.069 | uM | ALA5108779 | 7.16 | nM | Middle East respiratory syndrome-related coronavirus | ||
20. | ALA5205032 | 1; GS-5734 | Ratio | = | 5.3 | ALA5108778 | Severe acute respiratory syndrome coronavirus 2 |