# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5205337 | B2 | MIC80 | = | 2 | ug ml-1 | ALA5161924 | ug.mL-1 | Candida albicans | |||
2. | ALA5205337 | B2 | MIC80 | = | 2 | ug ml-1 | ALA5161923 | ug.mL-1 | Candida albicans | |||
3. | ALA5205337 | B2 | MIC80 | = | 1 | ug ml-1 | ALA5161922 | ug.mL-1 | Candida albicans | |||
4. | ALA5205337 | B2 | MIC80 | = | 2 | ug ml-1 | ALA5161921 | ug.mL-1 | Candida albicans | |||
5. | ALA5205337 | B2 | MIC80 | = | 2 | ug ml-1 | ALA5161920 | ug.mL-1 | Candida albicans | |||
6. | ALA5205337 | B2 | MIC80 | = | 1 | ug ml-1 | ALA5161919 | ug.mL-1 | Candida albicans | |||
7. | ALA5205337 | B2 | INH | = | 39.8 | % | ALA5161894 | % | Homo sapiens | |||
8. | ALA5205337 | B2 | INH | = | 76.6 | % | ALA5161893 | % | Homo sapiens | |||
9. | ALA5205337 | B2 | INH | = | 25.4 | % | ALA5161892 | % | Homo sapiens | |||
10. | ALA5205337 | B2 | INH | = | 39.2 | % | ALA5161891 | % | Homo sapiens | |||
11. | ALA5205337 | B2 | INH | = | 12 | % | ALA5161890 | % | Homo sapiens | |||
12. | ALA5205337 | B2 | t1/2 | > | 4.8 | hr | ALA5161888 | hr | ||||
13. | ALA5205337 | B2 | Stability | = | 90.6 | % | ALA5161886 | % | ||||
14. | ALA5205337 | B2 | Stability | = | 37.9 | % | ALA5161884 | % | ||||
15. | ALA5205337 | B2 | CLH | = | 28.8 | uL/min/kg | ALA5161882 | mL.min-1.kg-1 | ||||
16. | ALA5205337 | B2 | CLH | = | 32 | uL/min/kg | ALA5161880 | mL.min-1.kg-1 | ||||
17. | ALA5205337 | B2 | t1/2 | = | 43.3 | min | ALA5161878 | hr | ||||
18. | ALA5205337 | B2 | Kd | > | 25 | uM | ALA5161877 | nM | Homo sapiens | |||
19. | ALA5205337 | B2 | Kd | = | 0.139 | uM | ALA5161876 | 6.86 | nM | |||
20. | ALA5205337 | B2 | IC50 | = | 4.06 | uM | ALA5161853 | 5.39 | nM | Mus musculus |