# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5205388 | 12a; CCT373566 | T/C | = | 0.6 | ALA5168592 | Homo sapiens | |||||
2. | ALA5205388 | 12a; CCT373566 | Activity | 0 | ALA5168591 | Active | Homo sapiens | |||||
3. | ALA5205388 | 12a; CCT373566 | Activity | 0 | ALA5168590 | Active | ||||||
4. | ALA5205388 | 12a; CCT373566 | Fu | > | 0.09 | nM | ALA5168589 | nM | ||||
5. | ALA5205388 | 12a; CCT373566 | Activity | 0 | ALA5168588 | Non-Toxic | ||||||
6. | ALA5205388 | 12a; CCT373566 | PPB | = | 99.88 | % | ALA5168587 | % | ||||
7. | ALA5205388 | 12a; CCT373566 | F | = | 44 | % | ALA5168586 | % | ||||
8. | ALA5205388 | 12a; CCT373566 | Vdss | = | 0.47 | L/Kg | ALA5168585 | L.kg-1 | ||||
9. | ALA5205388 | 12a; CCT373566 | t1/2 | = | 1.15 | hr | ALA5168584 | hr | ||||
10. | ALA5205388 | 12a; CCT373566 | CL free | = | 4670 | ml/min.kg | ALA5168583 | mL.min-1.kg-1 | ||||
11. | ALA5205388 | 12a; CCT373566 | CLH | = | 6 | % | ALA5168582 | % | ||||
12. | ALA5205388 | 12a; CCT373566 | CL | = | 5.7 | ml/min.kg | ALA5168581 | mL.min-1.kg-1 | ||||
13. | ALA5205388 | 12a; CCT373566 | Cmax | = | 3947 | nM/L | ALA5168580 | nM | ||||
14. | ALA5205388 | 12a; CCT373566 | GI50 | = | 1900 | nM | ALA5168579 | nM | Homo sapiens | |||
15. | ALA5205388 | 12a; CCT373566 | GI50 | = | 12.5 | nM | ALA5168578 | nM | Homo sapiens | |||
16. | ALA5205388 | 12a; CCT373566 | GI50 | = | 8 | nM | ALA5168577 | nM | Homo sapiens | |||
17. | ALA5205388 | 12a; CCT373566 | GI50 | = | 1.4 | nM | ALA5168576 | nM | Homo sapiens | |||
18. | ALA5205388 | 12a; CCT373566 | GI50 | = | 2.1 | nM | ALA5168575 | nM | Homo sapiens | |||
19. | ALA5205388 | 12a; CCT373566 | Emax | = | 85 | % | ALA5168574 | % | Homo sapiens | |||
20. | ALA5205388 | 12a; CCT373566 | EC50 | = | 1 | nM | ALA5168573 | 9.00 | nM | Homo sapiens |