Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	NAMPT PROTAC B4	B4	IC50	=	100	nM	ALA5153533	7.00		nM	Homo sapiens
2.	NAMPT PROTAC B4	B4	Activity		0		ALA5153532		Active
3.	NAMPT PROTAC B4	B4	Activity		0		ALA5153530		Non-Toxic
4.	NAMPT PROTAC B4	B4	TGI	=	73	%	ALA5153529			%	Homo sapiens
5.	NAMPT PROTAC B4	B4	TGI	=	53	%	ALA5153528			%	Homo sapiens
6.	NAMPT PROTAC B4	B4	Activity		0		ALA5153527		Dde		Homo sapiens
7.	NAMPT PROTAC B4	B4	MRT	=	12.67	hr	ALA5153526			hr
8.	NAMPT PROTAC B4	B4	AUC	=	1111.92	hr.ng/ml	ALA5153525			ng.hr.mL-1
9.	NAMPT PROTAC B4	B4	Cmax	=	175.47	ng/ml	ALA5153524		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
10.	NAMPT PROTAC B4	B4	Tmax	=	4	hr	ALA5153523			hr
11.	NAMPT PROTAC B4	B4	t1/2	=	9.81	hr	ALA5153522			hr
12.	NAMPT PROTAC B4	B4	Activity		0		ALA5153521		Active		Homo sapiens
13.	NAMPT PROTAC B4	B4	Drug uptake		0		ALA5153518		NA
14.	NAMPT PROTAC B4	B4	Drug uptake		0		ALA5153517		Active
15.	NAMPT PROTAC B4	B4	Drug uptake		0		ALA5153516		Active
16.	NAMPT PROTAC B4	B4	Stability		0		ALA5153515		Stable	%
17.	NAMPT PROTAC B4	B4	deltaTm	>	2.62	degrees C	ALA5153514			degrees C	Homo sapiens
18.	NAMPT PROTAC B4	B4	deltaTm	=	5.11	degrees C	ALA5153513			degrees C	Homo sapiens
19.	NAMPT PROTAC B4	B4	Activity		0		ALA5153512		NA		Homo sapiens
20.	NAMPT PROTAC B4	B4	Activity		0		ALA5153509		Active		Homo sapiens