# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5206873 | 22 | F | = | 100 | % | ALA5126306 | % | ||||
2. | ALA5206873 | 22 | Vdss | = | 1.7 | L/Kg | ALA5126305 | L.kg-1 | ||||
3. | ALA5206873 | 22 | CL | = | 7 | ml/min.kg | ALA5126304 | mL.min-1.kg-1 | ||||
4. | ALA5206873 | 22 | AUC | = | 40 | uM.hr | ALA5126303 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
5. | ALA5206873 | 22 | Cmax | = | 5 | uM | ALA5126302 | nM | ||||
6. | ALA5206873 | 22 | PB | = | 95.7 | % | ALA5126301 | % | ||||
7. | ALA5206873 | 22 | PB | = | 95.7 | % | ALA5126300 | % | ||||
8. | ALA5206873 | 22 | PB | = | 94.7 | % | ALA5126299 | % | ||||
9. | ALA5206873 | 22 | Stability | = | 85 | % | ALA5126298 | % | ||||
10. | ALA5206873 | 22 | Stability | = | 91 | % | ALA5126297 | % | ||||
11. | ALA5206873 | 22 | Stability | = | 100 | % | ALA5126296 | % | Homo sapiens | |||
12. | ALA5206873 | 22 | Ratio IC50 | = | 208 | ALA5126295 | ||||||
13. | ALA5206873 | 22 | Ratio IC50 | = | 123 | ALA5126294 | ||||||
14. | ALA5206873 | 22 | IC50 | = | 2740 | nM | ALA5126293 | 5.56 | nM | Homo sapiens | ||
15. | ALA5206873 | 22 | IC50 | = | 6250 | nM | ALA5126292 | 5.20 | nM | Homo sapiens | ||
16. | ALA5206873 | 22 | IC50 | = | 126 | nM | ALA5126289 | 6.90 | nM | Mus musculus | ||
17. | ALA5206873 | 22 | IC50 | = | 19 | nM | ALA5126288 | 7.72 | nM | Homo sapiens |